Detalles de la búsqueda
1.
Design, synthesis, biological evaluation and docking study of some new aryl and heteroaryl thiomannosides as FimH antagonists.
Bioorg Chem
; 145: 107258, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38447463
2.
The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells.
J Immunol
; 206(11): 2544-2551, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33990399
3.
Synthesis, biological evaluation and molecular docking study of some new 4-aminosalicylic acid derivatives as anti-inflammatory and antimycobacterial agents.
Bioorg Chem
; 132: 106344, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36669356
4.
The design, synthesis, biological evaluation, and molecular docking of new 5-aminosalicylamide-4-thiazolinone hybrids as anticancer agents.
Arch Pharm (Weinheim)
; 356(10): e2300315, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37551741
5.
Further insight into the dual COX-2 and 15-LOX anti-inflammatory activity of 1,3,4-thiadiazole-thiazolidinone hybrids: The contribution of the substituents at 5th positions is size dependent.
Bioorg Chem
; 97: 103657, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32086052
6.
Click chemistry synthesis, biological evaluation and docking study of some novel 2'-hydroxychalcone-triazole hybrids as potent anti-inflammatory agents.
Bioorg Chem
; 95: 103505, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31901755
7.
Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
Bioorg Chem
; 94: 103378, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31677858
8.
Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors.
Bioorg Chem
; 104: 104260, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32920363
9.
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types.
Invest New Drugs
; 37(2): 252-261, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29947013
10.
Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.
Biochem Biophys Res Commun
; 495(1): 854-859, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29146181
11.
Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
Bioorg Chem
; 80: 461-471, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29986191
12.
Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
Bioorg Chem
; 78: 80-93, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29550533
13.
Design and synthesis of novel 5-aminosalicylate (5-ASA)-4-thiazolinone hybrid derivatives with promising antiproliferative activity.
Bioorg Med Chem Lett
; 26(7): 1647-50, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26947606
14.
Nature-inspired design of tetraindoles: Optimization of the core structure and evaluation of structure-activity relationship.
Bioorg Med Chem Lett
; 26(18): 4497-4503, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27503685
15.
Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives.
iScience
; 27(1): 108659, 2024 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38235331
16.
New nitazoxanide derivatives: design, synthesis, biological evaluation, and molecular docking studies as antibacterial and antimycobacterial agents.
RSC Med Chem
; 14(12): 2714-2730, 2023 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38107181
17.
Ionic liquid of ketoprofen-piperine modulates the pharmaceutical and therapeutic characters of ketoprofen.
Int J Pharm
; 620: 121724, 2022 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35405279
18.
The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45-/- immunodeficient B cells.
Sci Signal
; 15(723): eabf9570, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35230871
19.
Crystal structure and Hirshfeld surface analysis of 5-acetyl-3-amino-6-methyl-N-phenyl-4-[(E)-2-phenyl-ethen-yl]thieno[2,3-b]pyridine-2-carbox-amide.
Acta Crystallogr E Crystallogr Commun
; 78(Pt 2): 225-230, 2022 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35145756
20.
CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold.
Bioorg Med Chem
; 19(6): 1966-71, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21349726