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1.
Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.
Bioorg Chem
; 120: 105646, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35134645
2.
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer.
J Enzyme Inhib Med Chem
; 37(1): 2265-2282, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36000167
3.
Synthesis, in vitro biological investigation, and molecular dynamics simulations of thiazolopyrimidine based compounds as corticotrophin releasing factor receptor-1 antagonists.
Bioorg Chem
; 114: 105079, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34174633
4.
An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic properties.
Bioorg Med Chem
; 28(17): 115633, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32773088
5.
Design, Synthesis, Antitumor Activity and Molecular Docking Study of Novel 5-Deazaalloxazine Analogs.
Molecules
; 25(11)2020 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32481639
6.
Synthesis and in vitro anticancer evaluation of some fused indazoles, quinazolines and quinolines as potential EGFR inhibitors.
Bioorg Chem
; 89: 102985, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31121559
7.
Generation of a cell-permeable cycloheptapeptidyl inhibitor against the peptidyl-prolyl isomerase Pin1.
Org Biomol Chem
; 15(21): 4540-4543, 2017 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-28517007
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