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1.
2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights.
J Enzyme Inhib Med Chem
; 37(1): 349-372, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34923887
2.
Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells.
Nucleic Acids Res
; 39(9): 3607-20, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21227924
3.
TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor.
Mol Cancer Ther
; 21(7): 1090-1102, 2022 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35439320
4.
Discovery of 4-alkoxy-2-aryl-6,7-dimethoxyquinolines as a new class of topoisomerase I inhibitors endowed with potent in vitro anticancer activity.
Eur J Med Chem
; 215: 113261, 2021 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33631697
5.
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1.
Nucleic Acids Res
; 35(13): 4474-84, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17576665
6.
Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2.
Mol Cancer Ther
; 7(8): 2445-54, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18723490
7.
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.
J Cell Biol
; 195(5): 739-49, 2011 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-22123861
8.
The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells.
Cancer Res
; 69(3): 948-57, 2009 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19176392
9.
Novel indenoisoquinolines NSC 725776 and NSC 724998 produce persistent topoisomerase I cleavage complexes and overcome multidrug resistance.
Cancer Res
; 67(21): 10397-405, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17974983
10.
Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.
Mol Pharmacol
; 70(3): 1109-20, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16798938
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