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1.
Safety Assessment of Formulation Vehicles Following Intravitreal Administration in Rabbits.
Pharm Res
; 35(9): 173, 2018 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29987391
2.
Application of electroretinography (ERG) in early drug development for assessing retinal toxicity in rats.
Toxicol Appl Pharmacol
; 289(3): 525-33, 2015 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26482841
3.
Intermittent oral coadministration of a gamma secretase inhibitor with dexamethasone mitigates intestinal goblet cell hyperplasia in rats.
Toxicol Pathol
; 42(2): 422-34, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-23651588
4.
miR-208a as a biomarker of isoproterenol-induced cardiac injury in Sod2+/- and C57BL/6J wild-type mice.
Toxicol Pathol
; 42(7): 1117-29, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24713317
5.
An assessment of the ocular safety of excipient maleic acid following intravitreal injection in rabbits.
Toxicol Pathol
; 40(5): 797-806, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22552388
6.
A tyrosine kinase inhibitor-induced myocardial degeneration in rats through off-target phosphodiesterase inhibition.
J Appl Toxicol
; 32(12): 1008-20, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22936366
7.
Cardiovascular effects in rats following exposure to a receptor tyrosine kinase inhibitor.
Toxicol Pathol
; 38(3): 416-28, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20231546
8.
Corneal neovascularization and ocular irritancy responses in dogs following topical ocular administration of an EP4-prostaglandin E2 agonist.
Toxicol Pathol
; 37(7): 911-20, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20008547
9.
Editor's Highlight: Plasma miR-183/96/182 Cluster and miR-124 are Promising Biomarkers of Rat Retinal Toxicity.
Toxicol Sci
; 152(2): 273-83, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27208084
10.
Lessons from (S)-6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an inhibitor of receptor tyrosine kinase c-Met with high protein kinase selectivity but broad phosphodiesterase family inhibition leading to myocardial degeneration in rats.
J Med Chem
; 56(17): 6651-65, 2013 Sep 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-23944843
11.
Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer.
J Med Chem
; 55(18): 8091-109, 2012 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22924734
12.
PD0325901, a mitogen-activated protein kinase kinase inhibitor, produces ocular toxicity in a rabbit animal model of retinal vein occlusion.
J Ocul Pharmacol Ther
; 25(6): 519-30, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19929595
13.
Cytomegalovirus MCK-2 controls mobilization and recruitment of myeloid progenitor cells to facilitate dissemination.
Blood
; 107(1): 30-8, 2006 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16046529
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