Detalles de la búsqueda
1.
Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations.
Toxicol Appl Pharmacol
; 283(2): 117-26, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25549870
2.
Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I.
Food Chem Toxicol
; 92: 104-16, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27016491
3.
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.
Toxicol Lett
; 243: 98-110, 2016 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26739637
4.
Chemical analysis of estragole in fennel based teas and associated safety assessment using the Margin of Exposure (MOE) approach.
Food Chem Toxicol
; 65: 147-54, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24384409
5.
The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.
Food Chem Toxicol
; 74: 28-34, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25218219
6.
Inhibition of methyleugenol bioactivation by the herb-based constituent nevadensin and prediction of possible in vivo consequences using physiologically based kinetic modeling.
Food Chem Toxicol
; 59: 564-71, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23831728
7.
Matrix-derived combination effect and risk assessment for estragole from basil-containing plant food supplements (PFS).
Food Chem Toxicol
; 62: 32-40, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23959103
8.
In vivo validation and physiologically based biokinetic modeling of the inhibition of SULT-mediated estragole DNA adduct formation in the liver of male Sprague-Dawley rats by the basil flavonoid nevadensin.
Mol Nutr Food Res
; 57(11): 1969-78, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23894034
9.
Matrix modulation of the bioactivation of estragole by constituents of different alkenylbenzene-containing herbs and spices and physiologically based biokinetic modeling of possible in vivo effects.
Toxicol Sci
; 129(1): 174-87, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22649189
Resultados
1 -
9
de 9
1
Próxima >
>>