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Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages.
J Enzyme Inhib Med Chem
; 38(1): 2243551, 2023 Dec.
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| MEDLINE | ID: mdl-37558232
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