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1.
Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers.
Bioorg Med Chem Lett
; 95: 129485, 2023 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37714498
2.
Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor.
Bioorg Med Chem
; 31: 115969, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33422910
3.
Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFV600Einhibitors.
Bioorg Chem
; 106: 104508, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33280830
4.
New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011-2021) focussing on structure-activity relationship (SAR) and docking insights.
J Enzyme Inhib Med Chem
; 36(1): 1574-1602, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34233563
5.
Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking.
Bioorg Med Chem Lett
; 30(20): 127478, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32781217
6.
Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting V600EBRAF.
Bioorg Med Chem
; 28(11): 115493, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32340792
7.
Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening.
Bioorg Chem
; 100: 103967, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32470760
8.
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.
Bioorg Med Chem
; 27(7): 1159-1194, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30826188
9.
Design, synthesis, and anticancer activity of imidazo[2,1-b]oxazole-based RAF kinase inhibitors.
Bioorg Chem
; 93: 103349, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31627060
10.
ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation.
bioRxiv
; 2024 Jan 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38293213
11.
Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Eur J Med Chem
; 261: 115779, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37776574
12.
Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies.
Pharmaceuticals (Basel)
; 15(9)2022 Aug 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36145271
13.
Structural optimization of 4-(imidazol-5-yl)pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: Synthesis, in vitro assays and in silico study.
Eur J Pharm Sci
; 171: 106115, 2022 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34995782
14.
Ligand-based design, molecular dynamics and ADMET studies of suggested SARS-CoV-2 Mpro inhibitors.
RSC Adv
; 11(8): 4523-4538, 2021 Jan 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35747608
15.
Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors.
Eur J Med Chem
; 215: 113277, 2021 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33601311
16.
Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity.
J Med Chem
; 64(10): 6877-6901, 2021 05 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-33999621
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