Detalles de la búsqueda
1.
New 2-oxoindole derivatives as multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitors.
Bioorg Chem
; 145: 107234, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38412650
2.
New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization.
Mol Divers
; 2023 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36790582
3.
Discovery of oxindole-based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation.
Arch Pharm (Weinheim)
; 356(2): e2200407, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36403191
4.
Combination of an Oxindole Derivative with (-)-ß-Elemene Alters Cell Death Pathways in FLT3/ITD+ Acute Myeloid Leukemia Cells.
Molecules
; 28(13)2023 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37446914
5.
Novel Inhibitor for Downstream Targeting of Transforming Growth Factor-ß Signaling to Suppress Epithelial to Mesenchymal Transition and Cell Migration.
Int J Mol Sci
; 23(9)2022 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35563439
6.
Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition.
Bioorg Med Chem Lett
; 30(19): 127458, 2020 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32755678
7.
HSP70 induction by bleomycin metal core analogs.
Bioorg Med Chem Lett
; 30(7): 127002, 2020 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32044184
8.
Interruption of Vif/Elongin C interaction: In silico and experimental elucidation of the underlying molecular mechanism of benzimidazole-based APOBEC3G stabilizers.
Bioorg Med Chem
; 28(8): 115409, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32169404
9.
In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors.
Molecules
; 25(21)2020 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33171861
10.
New SIRT2 inhibitors: Histidine-based bleomycin spin-off.
Bioorg Med Chem
; 27(9): 1767-1775, 2019 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30885568
11.
Discovery of novel thienoquinoline-2-carboxamide chalcone derivatives as antiproliferative EGFR tyrosine kinase inhibitors.
Bioorg Med Chem
; 27(6): 1076-1086, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30744932
12.
Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement.
Molecules
; 24(18)2019 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31510043
13.
The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities.
Biol Pharm Bull
; 41(4): 570-574, 2018 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29386476
14.
Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.
Molecules
; 23(1)2017 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29280989
15.
Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system.
Bioorg Med Chem
; 23(17): 5476-82, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26260338
16.
Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition.
Front Chem
; 12: 1387923, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38800576
17.
Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor.
Pharmaceuticals (Basel)
; 17(5)2024 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38794229
18.
New nitric oxide donating 1,2,4-triazole/oxime hybrids: synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities.
Bioorg Med Chem
; 21(13): 3839-49, 2013 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23665142
19.
Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemia.
BMC Chem
; 17(1): 73, 2023 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37438819
20.
Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity.
ACS Omega
; 8(7): 6968-6981, 2023 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36844536