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1-(2-Hydroxy-5-((trimethylsilyl)ethynyl)phenyl)ethanone based α,ß-unsaturated derivatives an alternate to non-sulfonamide carbonic anhydrase II inhibitors, synthesis via Sonogashira coupling, binding analysis, Lipinsk's rule validation.
Bioorg Chem
; 84: 170-176, 2019 03.
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en Inglés
| MEDLINE | ID: mdl-30502628
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Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.
Bioorg Med Chem
; 26(12): 3707-3715, 2018 07 23.
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en Inglés
| MEDLINE | ID: mdl-29884581
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