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1.
Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome.
Hum Mol Genet
; 25(20): 4369-4375, 2016 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28173146
2.
Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).
Arch Biochem Biophys
; 631: 31-41, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28801166
3.
Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome.
Hum Mol Genet
; 26(22): 4540, 2017 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29036321
4.
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydroimid azo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, part 1.
Bioorg Med Chem Lett
; 21(15): 4422-8, 2011 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21737272
5.
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, part 2.
Bioorg Med Chem Lett
; 21(15): 4429-35, 2011 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21737263
6.
Synthesis and anti-hepatitis C virus activity of novel ethyl 1H-indole-3-carboxylates in vitro.
Bioorg Med Chem
; 18(16): 6143-8, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20638289
7.
Publisher Correction: 6-Bromoindirubin-3'-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice.
Sci Rep
; 10(1): 10232, 2020 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-32561809
8.
Synthesis and SAR of piperazinyl-N-phenylbenzamides as inhibitors of hepatitis C virus RNA replication in cell culture.
Bioorg Med Chem Lett
; 19(6): 1779-83, 2009 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19216075
9.
6-Bromoindirubin-3'-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice.
Sci Rep
; 9(1): 18091, 2019 12 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31792344
10.
A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.
J Med Chem
; 51(8): 2350-3, 2008 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-18370373
11.
Development and optimization of a binding assay for histone deacetylase 4 using surface plasmon resonance.
Anal Biochem
; 377(2): 267-9, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18381195
12.
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases.
Bioorg Med Chem Lett
; 18(6): 1814-9, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18308563
13.
2-Trifluoroacetylthiophene oxadiazoles as potent and selective class II human histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 18(23): 6083-7, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18930398
14.
Identification by High-Throughput Screening of Pseudomonas Acyl-Coenzyme A Synthetase Inhibitors.
SLAS Discov
; 22(7): 897-905, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28346095
15.
2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as inhibitors of the hepatitis C virus NS5B polymerase: discovery, SAR, modeling, and mutagenesis.
J Med Chem
; 49(5): 1693-705, 2006 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-16509585
16.
Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.
ACS Med Chem Lett
; 7(5): 454-9, 2016 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27190592
17.
Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.
J Med Chem
; 48(14): 4547-57, 2005 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-15999993
18.
HCV antiviral resistance: the impact of in vitro studies on the development of antiviral agents targeting the viral NS5B polymerase.
Antivir Chem Chemother
; 16(4): 225-45, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16130521
19.
Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni.
PLoS Negl Trop Dis
; 9(1): e0003484, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25635836
20.
Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin.
Exp Hematol
; 43(12): 1062-1071.e3, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26342260