Detalles de la búsqueda
1.
Model-Informed Clinical Practice - Determining an Appropriate Ampicillin-Sulbactam Redosing Regimen in Surgical Patients by Utilizing Population Pharmacokinetics and Target Attainment Analysis.
Antimicrob Agents Chemother
; 67(4): e0124822, 2023 04 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36920230
2.
Evaluation of Empirical Dosing Regimens for Meropenem in Intensive Care Unit Patients Using Population Pharmacokinetic Modeling and Target Attainment Analysis.
Antimicrob Agents Chemother
; 67(1): e0131222, 2023 01 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36622154
3.
Population pharmacokinetics and target attainment analyses to identify a rational empirical dosing strategy for cefepime in critically ill patients.
J Antimicrob Chemother
; 78(6): 1460-1470, 2023 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37071586
4.
Pharmacometric model of agalsidase-migalastat interaction in human: a novel mechanistic model of drug-drug interaction between a therapeutic protein and a small molecule.
J Pharmacokinet Pharmacodyn
; 50(1): 63-74, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36376611
5.
Population Pharmacokinetic-Pharmacodynamic Model of Oxfendazole in Healthy Adults in a Multiple Ascending Dose and Food Effect Study and Target Attainment Analysis.
Antimicrob Agents Chemother
; 66(1): e0143221, 2022 01 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34606333
6.
Population Pharmacokinetic Model of Oxfendazole and Metabolites in Healthy Adults following Single Ascending Doses.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33526484
7.
Comparing the performance of first-order conditional estimation (FOCE) and different expectation-maximization (EM) methods in NONMEM: real data experience with complex nonlinear parent-metabolite pharmacokinetic model.
J Pharmacokinet Pharmacodyn
; 48(4): 581-595, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33884580
8.
Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Adults in an Open-Label Phase 1 Multiple Ascending Dose and Food Effect Study.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32816721
9.
Population Pharmacokinetics of Linezolid in Tuberculosis Patients: Dosing Regimen Simulation and Target Attainment Analysis.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32778547
10.
Ethionamide Population Pharmacokinetic Model and Target Attainment in Multidrug-Resistant Tuberculosis.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32631828
11.
Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide Hydrolase.
J Pharmacol Exp Ther
; 374(1): 223-232, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32238455
12.
Cycloserine Population Pharmacokinetics and Pharmacodynamics in Patients with Tuberculosis.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30858211
13.
Fluoroquinolones in Drug-Resistant Tuberculosis: Culture Conversion and Pharmacokinetic/Pharmacodynamic Target Attainment To Guide Dose Selection.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31061152
14.
Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30745383
15.
Quantification of Cefepime, Meropenem, Piperacillin, and Tazobactam in Human Plasma Using a Sensitive and Robust Liquid Chromatography-Tandem Mass Spectrometry Method, Part 2: Stability Evaluation.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29941653
16.
Quantification of Cefepime, Meropenem, Piperacillin, and Tazobactam in Human Plasma Using a Sensitive and Robust Liquid Chromatography-Tandem Mass Spectrometry Method, Part 1: Assay Development and Validation.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29941654
17.
Development, validation, and potential applications of biotinylated red blood cells for posttransfusion kinetics and other physiological studies: evidenced-based analysis and recommendations.
Transfusion
; 58(8): 2068-2081, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29770455
18.
Triptolide induces Sertoli cell apoptosis in mice via ROS/JNK-dependent activation of the mitochondrial pathway and inhibition of Nrf2-mediated antioxidant response.
Acta Pharmacol Sin
; 39(2): 311-327, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28905938
19.
Estimation of adult and neonatal RBC lifespans in anemic neonates using RBCs labeled at several discrete biotin densities.
Pediatr Res
; 81(6): 905-910, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28099421
20.
TKI combination therapy: strategy to enhance dasatinib uptake by inhibiting Pgp- and BCRP-mediated efflux.
Biopharm Drug Dispos
; 37(7): 397-408, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27418107