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1.
Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPARγ agonists.
Bioorg Med Chem Lett
; 24(4): 1098-103, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24462665
2.
Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators.
Bioorg Med Chem Lett
; 20(4): 1399-404, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20079636
3.
Author Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody.
Sci Rep
; 10(1): 5097, 2020 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32184438
4.
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody.
Sci Rep
; 10(1): 1004, 2020 01 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-31969668
5.
Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.
J Med Chem
; 62(17): 7656-7668, 2019 09 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31403795
6.
Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist.
Arterioscler Thromb Vasc Biol
; 27(2): 359-65, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17110604
7.
Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.
J Med Chem
; 60(8): 3383-3404, 2017 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28398044
8.
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.
Diabetes
; 54(5): 1331-9, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15855317
9.
Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell.
Prostaglandins Other Lipid Mediat
; 80(1-2): 15-27, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16846783
10.
Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.
J Med Chem
; 59(6): 2452-67, 2016 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26938474
11.
Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors.
ACS Med Chem Lett
; 7(4): 379-84, 2016 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27096045
12.
Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.
Nat Med
; 22(2): 202-9, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26752518
13.
Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.
ACS Med Chem Lett
; 6(8): 919-24, 2015 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-26288694
14.
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.
J Med Chem
; 58(18): 7140-63, 2015 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26090771
15.
Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress.
Front Pharmacol
; 3: 128, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22783192
16.
Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment.
Clin Chem
; 54(6): 1038-45, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18436719
17.
Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine.
J Lipid Res
; 47(6): 1281-8, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16508037
18.
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation.
J Biol Chem
; 277(8): 6667-75, 2002 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-11741921
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