Detalles de la búsqueda
1.
Galectin-8 inhibition and functions in immune response and tumor biology.
Med Res Rev
; 2024 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38613488
2.
Discovery of two non-UDP-mimic inhibitors of O-GlcNAc transferase by screening a DNA-encoded library.
Bioorg Chem
; 147: 107321, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38604018
3.
Diminishing hERG inhibitory activity of aminopiperidine-naphthyridine linked NBTI antibacterials by structural and physicochemical optimizations.
Bioorg Chem
; 128: 106087, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35970069
4.
Discovery of a New Drug-like Series of OGT Inhibitors by Virtual Screening.
Molecules
; 27(6)2022 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35335358
5.
Combining cross-coupling reaction and Knoevenagel condensation in the synthesis of glyco-BODIPY probes for DC-SIGN super-resolution bioimaging.
Bioorg Chem
; 109: 104730, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33621778
6.
Overview of the Assays to Probe O-Linked ß-N-Acetylglucosamine Transferase Binding and Activity.
Molecules
; 26(4)2021 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33669256
7.
A New Cell-Based AI-2-Mediated Quorum Sensing Interference Assay in Screening of LsrK-Targeted Inhibitors.
Chembiochem
; 21(13): 1918-1922, 2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32026533
8.
Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors Differs among Cells and Is Not Required for Its Inhibition.
Molecules
; 25(15)2020 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32722493
9.
Mechanisms and pathways of anti-inflammatory activity of DPP-4 inhibitors in cardiovascular and renal protection.
Med Res Rev
; 39(1): 404-422, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29806214
10.
Rutin as Deoxyribonuclease I Inhibitor.
Chem Biodivers
; 16(5): e1900069, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-30883015
11.
STD NMR and molecular modelling insights into interaction of novel mannose-based ligands with DC-SIGN.
Org Biomol Chem
; 14(3): 862-75, 2016 Jan 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26580315
12.
Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.
Bioorg Med Chem
; 24(21): 5221-5234, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27601373
13.
Internalization and Accumulation in Dendritic Cells of a Small pH-Activatable Glycomimetic Fluorescent Probe as Revealed by Spectral Detection.
Chembiochem
; 16(18): 2660-7, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26515511
14.
The overview of development of novel bacterial topoisomerase inhibitors effective against multidrug-resistant bacteria in an academic environment: From early hits to in vivo active antibacterials.
Eur J Pharm Sci
; 192: 106632, 2024 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37949194
15.
Antimicrobial activity and cytotoxicity of some 2-amino-5-alkylidene-thiazol-4-ones.
Mol Divers
; 17(4): 773-80, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24062019
16.
Exploring Alternative Pathways to Target Bacterial Type II Topoisomerases Using NBTI Antibacterials: Beyond Halogen-Bonding Interactions.
Antibiotics (Basel)
; 12(5)2023 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37237833
17.
Design of OSMI-4 Analogs Using Scaffold Hopping: Investigating the Importance of the Uridine Mimic in the Binding of OGT Inhibitors.
ChemMedChem
; 18(8): e202300001, 2023 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36752318
18.
Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy.
Eur J Med Chem
; 250: 115160, 2023 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36753879
19.
The Structural Features of Novel Bacterial Topoisomerase Inhibitors That Define Their Activity on Topoisomerase IV.
J Med Chem
; 65(9): 6431-6440, 2022 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35503563
20.
Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors.
RSC Adv
; 12(29): 18973-18984, 2022 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35873334