Detalles de la búsqueda
1.
Computational Modeling of the Synergistic Role of GCN2 and HPA Axis in Regulating the Integrated Stress Response in the Central Circadian Timing System.
Physiol Genomics
; 2024 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38881429
2.
Circadian Effects of Drug Responses.
Annu Rev Biomed Eng
; 23: 203-224, 2021 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33788580
3.
Does seasonality of the microbiota contribute to the seasonality of acute gout flare?
Clin Exp Rheumatol
; 40(9): 1793-1800, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35383564
4.
Towards a comprehensive assessment of QSP models: what would it take?
J Pharmacokinet Pharmacodyn
; 2022 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35962928
5.
Two heads are better than one: current landscape of integrating QSP and machine learning : An ISoP QSP SIG white paper by the working group on the integration of quantitative systems pharmacology and machine learning.
J Pharmacokinet Pharmacodyn
; 49(1): 5-18, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35103884
6.
Pathway-level analysis of genome-wide circadian dynamics in diverse tissues in rat and mouse.
J Pharmacokinet Pharmacodyn
; 48(3): 361-374, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33768484
7.
Mathematical modeling informs the impact of changes in circadian rhythms and meal patterns on insulin secretion.
Am J Physiol Regul Integr Comp Physiol
; 317(1): R98-R107, 2019 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31042416
8.
The physiological significance of the circadian dynamics of the HPA axis: Interplay between circadian rhythms, allostasis and stress resilience.
Horm Behav
; 110: 77-89, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30862458
9.
Mathematical analysis of circadian disruption and metabolic re-entrainment of hepatic gluconeogenesis: the intertwining entraining roles of light and feeding.
Am J Physiol Endocrinol Metab
; 314(6): E531-E542, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29351477
10.
A framework for 2-stage global sensitivity analysis of GastroPlus™ compartmental models.
J Pharmacokinet Pharmacodyn
; 45(2): 309-327, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29423863
11.
Pharmacokinetics and Pharmacodynamics of Curcumin in regulating anti-inflammatory and epigenetic gene expression.
Biopharm Drug Dispos
; 39(6): 289-297, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29870054
12.
Pharmacokinetics and Pharmacodynamics of the Triterpenoid Ursolic Acid in Regulating the Antioxidant, Anti-inflammatory, and Epigenetic Gene Responses in Rat Leukocytes.
Mol Pharm
; 14(11): 3709-3717, 2017 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29035547
13.
On the analysis of complex biological supply chains: From Process Systems Engineering to Quantitative Systems Pharmacology.
Comput Chem Eng
; 107: 100-110, 2017 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29353945
14.
The role of the hypothalamic-pituitary-adrenal axis in modulating seasonal changes in immunity.
Physiol Genomics
; 48(10): 719-738, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27341833
15.
Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine.
J Pharmacokinet Pharmacodyn
; 43(5): 481-504, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27647273
16.
Human metabolic response to systemic inflammation: assessment of the concordance between experimental endotoxemia and clinical cases of sepsis/SIRS.
Crit Care
; 19: 71, 2015 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25887472
17.
Pharmacokinetics and pharmacodynamics of 3,3'-diindolylmethane (DIM) in regulating gene expression of phase II drug metabolizing enzymes.
J Pharmacokinet Pharmacodyn
; 42(4): 401-8, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26138223
18.
Bioinformatics analysis of transcriptional regulation of circadian genes in rat liver.
BMC Bioinformatics
; 15: 83, 2014 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-24666587
19.
Mathematical modeling of light-mediated HPA axis activity and downstream implications on the entrainment of peripheral clock genes.
Physiol Genomics
; 46(20): 766-78, 2014 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25073602
20.
Time-restricted feeding and the realignment of biological rhythms: translational opportunities and challenges.
J Transl Med
; 12: 79, 2014 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24674294