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1.
Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Proc Natl Acad Sci U S A
; 116(11): 5160-5169, 2019 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796190
2.
Oral Pretreatment with Galantamine Effectively Mitigates the Acute Toxicity of a Supralethal Dose of Soman in Cynomolgus Monkeys Posttreated with Conventional Antidotes.
J Pharmacol Exp Ther
; 375(1): 115-126, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32759369
3.
Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds.
J Pharmacol Exp Ther
; 350(2): 313-21, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24907067
4.
(R,S)-trihexyphenidyl, acting via a muscarinic receptor-independent mechanism, inhibits hippocampal glutamatergic and GABAergic synaptic transmissions: Potential relevance for treatment of organophosphorus intoxication.
Neuropharmacology
; 239: 109684, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37549771
5.
Pretreatment of Guinea pigs with galantamine prevents immediate and delayed effects of soman on inhibitory synaptic transmission in the hippocampus.
J Pharmacol Exp Ther
; 334(3): 1051-8, 2010 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20554906
6.
Gestational exposures to organophosphorus insecticides: From acute poisoning to developmental neurotoxicity.
Neuropharmacology
; 180: 108271, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32814088
7.
(2R,6R)-hydroxynorketamine rapidly potentiates hippocampal glutamatergic transmission through a synapse-specific presynaptic mechanism.
Neuropsychopharmacology
; 45(2): 426-436, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31216563
8.
Acute toxicity of organophosphorus compounds in guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition.
J Pharmacol Exp Ther
; 328(2): 516-24, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18984651
9.
A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus.
J Pharmacol Exp Ther
; 328(1): 69-82, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18842705
10.
Effectiveness of donepezil, rivastigmine, and (+/-)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamine.
J Pharmacol Exp Ther
; 331(3): 1014-24, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19741148
11.
Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors.
J Med Chem
; 46(7): 1144-52, 2003 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-12646025
12.
Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon.
Neurotoxicology
; 25(3): 481-94, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15019311
13.
An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint.
Neurotoxicology
; 31(1): 77-84, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19883683
14.
Molecular and cellular actions of galantamine: clinical implications for treatment of organophosphorus poisoning.
J Mol Neurosci
; 40(1-2): 196-203, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19690988
15.
Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman.
Neurotoxicology
; 31(1): 67-76, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19782102
16.
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
Proc Natl Acad Sci U S A
; 103(35): 13220-5, 2006 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-16914529
17.
Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons.
J Pharmacol Exp Ther
; 312(3): 1195-205, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15522999
18.
The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system.
Mol Pharmacol
; 61(5): 1222-34, 2002 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-11961141
19.
Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors.
J Pharmacol Exp Ther
; 304(1): 254-65, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12490599
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