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1.
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
Liver Int
; 44(2): 433-445, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38010893
2.
Increased levels and activation of the IL-17 receptor in microglia contribute to enhanced neuroinflammation in cerebellum of hyperammonemic rats.
Biol Res
; 57(1): 18, 2024 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38671534
3.
Patients who died with steatohepatitis or liver cirrhosis show neuroinflammation and neuronal loss in hippocampus.
Eur J Neurol
; 30(10): 3032-3046, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37340928
4.
Enhanced Activation of the S1PR2-IL-1ß-Src-BDNF-TrkB Pathway Mediates Neuroinflammation in the Hippocampus and Cognitive Impairment in Hyperammonemic Rats.
Int J Mol Sci
; 24(24)2023 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38139078
5.
The S1PR2-CCL2-BDNF-TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia.
Neuropathol Appl Neurobiol
; 48(4): e12799, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35152448
6.
Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia.
Int J Mol Sci
; 23(19)2022 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36233065
7.
Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-α treatment.
J Hepatol
; 73(3): 582-592, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30654069
8.
Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κß pathway.
J Neuroinflammation
; 17(1): 269, 2020 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32917219
9.
Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-κB pathway.
J Neuroinflammation
; 17(1): 70, 2020 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-32087723
10.
Differential role of interleukin-1ß in neuroinflammation-induced impairment of spatial and nonspatial memory in hyperammonemic rats.
FASEB J
; 33(9): 9913-9928, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31162953
11.
Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms.
J Neuroinflammation
; 15(1): 36, 2018 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29422059
12.
Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications.
Front Pharmacol
; 15: 1358323, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38560359
13.
Sustained Hyperammonemia Activates NF-κB in Purkinje Neurons Through Activation of the TrkB-PI3K-AKT Pathway by Microglia-Derived BDNF in a Rat Model of Minimal Hepatic Encephalopathy.
Mol Neurobiol
; 60(6): 3071-3085, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36790604
14.
Hepatic encephalopathy: investigational drugs in preclinical and early phase development.
Expert Opin Investig Drugs
; 32(11): 1055-1069, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37902074
15.
Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms.
Mol Neurobiol
; 56(6): 4428-4439, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30328550
16.
Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP.
Neuropharmacology
; 161: 107496, 2019 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30641078
17.
Peripheral inflammation induces neuroinflammation that alters neurotransmission and cognitive and motor function in hepatic encephalopathy: Underlying mechanisms and therapeutic implications.
Acta Physiol (Oxf)
; 226(2): e13270, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30830722
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