Detalles de la búsqueda
1.
Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor.
Mol Pharmacol
; 104(3): 115-131, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37316350
2.
The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor.
Anesth Analg
; 137(3): 691-701, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37058425
3.
Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators.
Molecules
; 28(3)2023 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36770942
4.
Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors?
Molecules
; 26(8)2021 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33917953
5.
Nicotine smoking concentrations modulate GABAergic synaptic transmission in murine medial prefrontal cortex by activation of α7* and ß2* nicotinic receptors.
Eur J Neurosci
; 51(3): 781-792, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31613395
6.
Alkaloids Purified from Aristotelia chilensis Inhibit the Human α3ß4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α4ß2 and α7 Subtypes.
J Nat Prod
; 82(7): 1953-1960, 2019 07 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31276409
7.
Drimane Sesquiterpenoids Noncompetitively Inhibit Human α4ß2 Nicotinic Acetylcholine Receptors with Higher Potency Compared to Human α3ß4 and α7 Subtypes.
J Nat Prod
; 81(4): 811-817, 2018 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29634269
8.
Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4ß2 and α3ß4 subtypes.
Biochim Biophys Acta
; 1848(2): 731-41, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25475645
9.
The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in Mice.
Anesth Analg
; 121(5): 1369-77, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26280585
10.
Molecular interactions between mecamylamine enantiomers and the transmembrane domain of the human α4ß2 nicotinic receptor.
Biochemistry
; 53(5): 908-18, 2014 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24437521
11.
To what extent may aminochrome increase the vulnerability of dopaminergic neurons in the context of Parkinson's disease.
Int J Biochem Cell Biol
; 168: 106528, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38246261
12.
Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABAA receptor and CaV2.2 channel.
Biochem Pharmacol
; 223: 116183, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38580167
13.
The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation.
Eur J Pharmacol
; 966: 176329, 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38253116
14.
Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of α6-Nicotinic Receptors and Dopamine Transporters.
ACS Chem Neurosci
; 15(9): 1738-1754, 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38613458
15.
Differential pharmacological activity of JN403 between α7 and muscle nicotinic acetylcholine receptors.
Biochemistry
; 52(47): 8480-8, 2013 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-24164482
16.
Functional and structural interaction of (-)-reboxetine with the human α4ß2 nicotinic acetylcholine receptor.
J Pharmacol Exp Ther
; 344(1): 113-23, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23010362
17.
α7 Nicotinic acetylcholine receptor potentiation downregulates chemotherapy-induced inflammatory overactivation by overlapping intracellular mechanisms.
Int J Biochem Cell Biol
; 158: 106405, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36966906
18.
(+)-Catharanthine and (-)-18-methoxycoronaridine induce antidepressant-like activity in mice by differently recruiting serotonergic and norepinephrinergic neurotransmission.
Eur J Pharmacol
; 939: 175454, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36549498
19.
Coronaridine congeners induce sedative and anxiolytic-like activity in naïve and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA.
Eur J Pharmacol
; 953: 175854, 2023 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37331683
20.
Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABAA Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic Receptor.
Biomolecules
; 13(4)2023 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37189445