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1.
Absorption and cleavage of enalapril, a carboxyl ester prodrug, in the rat intestine: in vitro, in situ intestinal perfusion and portal vein cannulation models.
Biopharm Drug Dispos
; 36(6): 385-397, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25832562
2.
Characterization of recombinantly expressed rat and monkey intestinal alkaline phosphatases: in vitro studies and in vivo correlations.
Drug Metab Dispos
; 41(7): 1425-32, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23633529
3.
Drug-drug interaction study to assess the effects of atorvastatin co-administration on pharmacokinetics and anti-thrombotic properties of cilostazol in male Wistar rats.
Biopharm Drug Dispos
; 33(8): 455-65, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22936637
4.
Improving Drug Delivery While Tailoring Prodrug Activation to Modulate Cmax and Cmin by Optimization of (Carbonyl)oxyalkyl Linker-Based Prodrugs of Atazanavir.
J Med Chem
; 65(16): 11150-11176, 2022 08 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35952307
5.
(Carbonyl)oxyalkyl linker-based amino acid prodrugs of the HIV-1 protease inhibitor atazanavir that enhance oral bioavailability and plasma trough concentration.
Eur J Med Chem
; 207: 112749, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33065417
6.
Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir.
J Med Chem
; 62(7): 3553-3574, 2019 04 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30938524
7.
Coupling of an Acyl Migration Prodrug Strategy with Bio-activation To Improve Oral Delivery of the HIV-1 Protease Inhibitor Atazanavir.
J Med Chem
; 61(9): 4176-4188, 2018 05 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29693401
8.
Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation.
Sci Pharm
; 80(3): 633-46, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23008811
9.
Effect of multidose cilostazol on pharmacokinetic and lipid profile of atorvastatin in male Wistar rats.
J Pharm Pharmacol
; 64(11): 1638-45, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23058051
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