Detalles de la búsqueda
1.
Alphav and beta1 integrins regulate dynamic compression-induced proteoglycan synthesis in 3D gel culture by distinct complementary pathways.
Osteoarthritis Cartilage
; 18(2): 249-56, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19800448
2.
Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation.
Osteoarthritis Cartilage
; 17(5): 627-35, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19026578
3.
Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.
Science
; 284(5420): 1664-6, 1999 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-10356395
4.
Modification of red cell membrane structure by cholesterol-rich lipid dispersions. A model for the primary spur cell defect.
J Clin Invest
; 55(1): 115-26, 1975 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-162782
5.
Effect of interleukin-1 on the size distribution of cartilage proteoglycans as determined by sedimentation field flow fractionation.
Biochim Biophys Acta
; 993(1): 100-7, 1989 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-2804117
6.
Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors.
J Med Chem
; 44(21): 3347-50, 2001 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-11585439
7.
Aggrecanase. A target for the design of inhibitors of cartilage degradation.
Ann N Y Acad Sci
; 878: 92-107, 1999 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-10415722
8.
Effect of animal age and chronicity of interleukin-1 exposure on cartilage proteoglycan depletion in vivo.
J Orthop Res
; 12(3): 321-30, 1994 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-8207585
9.
Macrocyclic amino carboxylates as selective MMP-8 inhibitors.
J Med Chem
; 41(11): 1749-51, 1998 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-9599226
10.
Eicosanoid production and cell accumulation induced by intrapleural injection of sodium arachidonate in the rat. Characterization of the model.
Biochem Pharmacol
; 38(22): 4151-4, 1989 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-2557040
11.
Long-term nitrogen dioxide exposure: effects on lung lipids and mechanical properties.
Arch Environ Health
; 26(3): 156-60, 1973 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-4688855
12.
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
Arthritis Rheum
; 34(8): 1006-13, 1991 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-1859477
13.
Signal transduction through chondrocyte integrin receptors induces matrix metalloproteinase synthesis and synergizes with interleukin-1.
Arthritis Rheum
; 38(9): 1304-14, 1995 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-7575726
14.
Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis, and prostaglandin E2 release from cartilage in organ culture.
Arthritis Rheum
; 32(3): 288-97, 1989 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-2784682
15.
Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase.
J Biol Chem
; 275(50): 39096-102, 2000 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-10991945
16.
Effect of ebselen on IL-1-induced alterations in cartilage metabolism.
Inflamm Res
; 47(3): 115-21, 1998 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-9562336
17.
Effects of IL-1 muteins on cartilage degradation and as inducers of acute inflammation.
Agents Actions
; 34(1-2): 60-2, 1991 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-1793052
18.
Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2.
Exp Cell Res
; 206(1): 58-62, 1993 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-8482360
19.
Interleukin-1 receptor antagonist inhibits proteoglycan breakdown in antigen induced but not polycation induced arthritis in the rabbit.
J Rheumatol
; 22(7): 1338-46, 1995 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-7562769
20.
Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) is induced in rabbit articular chondrocytes by cotreatment with interleukin 1 beta and a protein kinase C activator.
Exp Cell Res
; 201(2): 245-9, 1992 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-1322311