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1.
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells.
Neuropharmacology
; 38(10): 1519-29, 1999 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-10530814
2.
(3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist.
J Med Chem
; 38(25): 4885-90, 1995 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-8523401
3.
Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.
J Med Chem
; 39(11): 2219-31, 1996 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-8667365
4.
Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, absolute stereochemical preferences, and in vivo activity.
J Med Chem
; 39(11): 2232-44, 1996 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-8667366
5.
NMDA antagonist activity of (+/-)-(2SR,4RS)-4-(1H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer.
J Med Chem
; 35(17): 3111-5, 1992 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-1387167
6.
2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 1. Effects of alkyl, arylalkyl, and diarylalkyl substitution.
J Med Chem
; 41(3): 346-57, 1998 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-9464366
7.
4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.
J Med Chem
; 34(1): 90-7, 1991 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-1825117
8.
6-substituted decahydroisoquinoline-3-carboxylic acids as potent and selective conformationally constrained NMDA receptor antagonists.
J Med Chem
; 35(19): 3547-60, 1992 Sep 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-1404235
9.
2-substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioavailability.
J Med Chem
; 41(3): 358-78, 1998 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-9464367
10.
Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists.
J Med Chem
; 41(15): 2709-19, 1998 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-9667962
11.
Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes.
Naunyn Schmiedebergs Arch Pharmacol
; 362(6): 546-54, 2000 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-11138847
12.
Beneficial effects of continuous subcutaneous insulin infusion in older patients with long-standing type 1 diabetes.
Endocr Pract
; 7(5): 364-9, 2001.
Artículo
en Inglés
| MEDLINE | ID: mdl-11585372
13.
In defense of Arnold's theory of emotion.
Psychol Bull
; 70(4): 283-4, 1968 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-5722570
14.
(3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist.
J Med Chem
; 36(14): 2046-8, 1993 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-8393116
15.
[3H]N-2-(4-(N-benzamido)phenyl)propyl-2-propanesulfonamide: a novel AMPA receptor potentiator and radioligand.
J Med Chem
; 44(3): 302-4, 2001 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11462971
16.
Biarylpropylsulfonamides as novel, potent potentiators of 2-amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic acid (AMPA) receptors.
J Med Chem
; 43(23): 4354-8, 2000 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-11087558
17.
Emotion, motivation, and the limbic system.
Ann N Y Acad Sci
; 159(3): 1041-58, 1969 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-4900682
18.
Taste of saccharin as sufficient reward for performance.
Psychol Rep
; 19(3): 1293-4, 1966 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-5956428
19.
[3H]LY341495, a highly potent, selective and novel radioligand for labeling Group II metabotropic glutamate receptors.
Bioorg Med Chem Lett
; 8(14): 1919-22, 1998 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-9873459
20.
[3H]LY341495 binding to group II metabotropic glutamate receptors in rat brain.
J Pharmacol Exp Ther
; 298(2): 453-60, 2001 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-11454905