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1.
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features.
Biol Chem
; 2024 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38373142
2.
Isolation of Antigen-Specific Unconventional Bovine Ultra-Long CDR3H Antibodies Using Cattle Immunization in Combination with Yeast Surface Display.
Methods Mol Biol
; 2681: 113-129, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37405646
3.
Affinity Maturation of the Natural Ligand (B7-H6) for Natural Cytotoxicity Receptor NKp30 by Yeast Surface Display.
Methods Mol Biol
; 2681: 231-248, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37405651
4.
Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format.
Front Immunol
; 14: 1238313, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37942319
5.
A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization.
MAbs
; 15(1): 2261149, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37766540
6.
NKp46-specific single domain antibodies enable facile engineering of various potent NK cell engager formats.
Protein Sci
; 32(3): e4593, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36775946
7.
Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition.
MAbs
; 15(1): 2236265, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37469014
8.
AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study.
Front Mol Biosci
; 10: 1249247, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37842638
9.
Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of 'Almost Natural' Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection.
Front Immunol
; 12: 801368, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-35087526
10.
Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity.
Front Immunol
; 12: 742418, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34759924
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