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1.
Prolyl isomerase Pin1 in skeletal muscles contributes to systemic energy metabolism and exercise capacity through regulating SERCA activity.
Biochem Biophys Res Commun
; 715: 150001, 2024 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38676996
2.
Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex.
Exp Cell Res
; 425(2): 113544, 2023 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36906101
3.
miR-582-5p targets Skp1 and regulates NF-κB signaling-mediated inflammation.
Arch Biochem Biophys
; 734: 109501, 2023 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36592647
4.
Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.
Int J Mol Sci
; 24(10)2023 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-37240193
5.
Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells.
Int J Mol Sci
; 24(21)2023 Nov 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37958994
6.
The hypoxia-inducible factor-α prolyl hydroxylase inhibitor FG4592 ameliorates renal fibrosis by inducing the H3K9 demethylase JMJD1A.
Am J Physiol Renal Physiol
; 323(5): F539-F552, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36074918
7.
Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells.
Int J Mol Sci
; 22(8)2021 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33919842
8.
Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.
Int J Mol Sci
; 20(19)2019 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31546603
9.
The prolyl isomerase Pin1 increases ß-cell proliferation and enhances insulin secretion.
J Biol Chem
; 292(28): 11886-11895, 2017 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28566287
10.
Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.
Mol Cell
; 39(4): 570-82, 2010 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-20797629
11.
Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages.
Mediators Inflamm
; 2018: 3062319, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30046278
12.
Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications.
Int J Mol Sci
; 19(10)2018 Oct 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30297626
13.
The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.
Int J Mol Sci
; 19(12)2018 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30544662
14.
USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.
Biochem Biophys Res Commun
; 484(3): 522-528, 2017 03 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28126338
15.
Reduced SHARPIN and LUBAC Formation May Contribute to CCl4- or Acetaminophen-Induced Liver Cirrhosis in Mice.
Int J Mol Sci
; 18(2)2017 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28165393
16.
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Int J Mol Sci
; 18(8)2017 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28777298
17.
Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.
J Biol Chem
; 290(40): 24255-66, 2015 Oct 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26276391
18.
IL-17A synergistically enhances TNFα-induced IL-6 and CCL20 production in 3T3-L1 adipocytes.
Biochem Biophys Res Commun
; 477(2): 241-6, 2016 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27311858
19.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Mediators Inflamm
; 2016: 8603164, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28070145
20.
Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.
Int J Mol Sci
; 17(9)2016 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27618008