Detalles de la búsqueda
1.
Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction.
Bioorg Med Chem
; 84: 117256, 2023 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37003157
2.
Tricyclic Pyrazole-Based Compounds as Useful Scaffolds for Cannabinoid CB1/CB2 Receptor Interaction.
Molecules
; 26(8)2021 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33917187
3.
Biological Effects on µ-Receptors Affinity and Selectivity of Arylpropenyl Chain Structural Modification on Diazatricyclodecane Derivatives.
Molecules
; 26(18)2021 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34576918
4.
Synthesis, biological evaluation and docking studies of a novel class of sulfur-bridged diazabicyclo[3.3.1]nonanes.
Bioorg Chem
; 102: 104072, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32693307
5.
Development of Oxygen-Bridged Pyrazole-Based Structures as Cannabinoid Receptor 1 Ligands.
Molecules
; 24(9)2019 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31035548
6.
Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB1 receptor ligand antagonists.
Bioorg Med Chem
; 26(1): 295-307, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29229226
7.
Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB2 receptor antagonists/inverse agonists.
Bioorg Med Chem
; 24(21): 5291-5301, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27624523
8.
Novel 1,3,4-oxadiazole chalcogen analogues: Synthesis and cytotoxic activity.
Eur J Med Chem
; 238: 114440, 2022 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35576700
9.
Synthesis and SAR study of new phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phosphodiesterase 10A inhibitors.
Bioorg Med Chem
; 19(1): 642-9, 2011 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21087867
10.
Synthesis and cytotoxicity of novel hexahydrothienocycloheptapyridazinone derivatives.
Molecules
; 14(9): 3494-508, 2009 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-19783939
11.
Novel N-aryl nicotinamide derivatives: Taking stock on 3,6-diazabicyclo[3.1.1]heptanes as ligands for neuronal acetylcholine receptors.
Eur J Med Chem
; 180: 51-61, 2019 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31299587
12.
Novel pyrrolocycloalkylpyrazole analogues as CB1 ligands.
Chem Biol Drug Des
; 91(1): 181-193, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28675787
13.
Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Typeâ 2 Ligands.
ChemMedChem
; 13(11): 1102-1114, 2018 06 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29575721
14.
Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α4ß2 nACh receptors.
Eur J Med Chem
; 152: 401-416, 2018 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29751234
15.
New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking.
Eur J Med Chem
; 127: 398-412, 2017 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28088085
16.
Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.
J Med Chem
; 59(23): 10451-10469, 2016 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27801583
17.
Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
Eur J Med Chem
; 112: 66-80, 2016 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-26890113
18.
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
J Med Chem
; 48(7): 2638-45, 2005 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-15801854
19.
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Eur J Pharmacol
; 516(3): 204-11, 2005 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15967425
20.
Determination of amphetamine-derived designer drugs in human urine by SPE extraction and capillary electrophoresis with mass spectrometry detection.
J Chromatogr B Analyt Technol Biomed Life Sci
; 814(1): 93-8, 2005 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-15607712