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1.
ß-Alanine and N-terminal cationic substituents affect polyamide-DNA binding.
Org Biomol Chem
; 15(46): 9880-9888, 2017 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-29143012
2.
Modulation of DNA-polyamide interaction by ß-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.
Org Biomol Chem
; 12(38): 7523-36, 2014 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25141096
3.
Correlation of local effects of DNA sequence and position of ß-alanine inserts with polyamide-DNA complex binding affinities and kinetics.
Biochemistry
; 51(49): 9796-806, 2012 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23167504
4.
Fluorescence assay of polyamide-DNA interactions.
Anal Biochem
; 423(1): 178-83, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22342620
5.
The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part III: the three microdose candidates.
Bioorg Med Chem Lett
; 20(23): 7164-8, 2010 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20728356
6.
Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Bioorg Med Chem Lett
; 20(2): 576-80, 2010 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20005097
7.
Computer-Aided Design (CAD) of Synzymes: Use of Molecular Mechanics (MM) for the Rational Design of Superoxide Dismutase Mimics.
Inorg Chem
; 38(8): 1908-1917, 1999 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-11670965
8.
DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral Agents.
Med Chem (Los Angeles)
; 4: 338-344, 2014 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-24839583
9.
Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature.
Chem Commun (Camb)
; 49(76): 8543-5, 2013 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23945614
10.
Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with ß-alanine.
Biochimie
; 95(2): 271-9, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23023196
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