Búsqueda | Biblioteca Virtual en Salud

1.

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

Sykes, Stephen M; Lane, Steven W; Bullinger, Lars; Kalaitzidis, Demetrios; Yusuf, Rushdia; Saez, Borja; Ferraro, Francesca; Mercier, Francois; Singh, Harshabad; Brumme, Kristina M; Acharya, Sanket S; Scholl, Claudia; Schöll, Claudia; Tothova, Zuzana; Attar, Eyal C; Fröhling, Stefan; DePinho, Ronald A; Armstrong, Scott A; Gilliland, D Gary; Scadden, David T.

Cell ; 146(5): 697-708, 2011 Sep 02.

Artículo en Inglés | MEDLINE | ID: mdl-21884932

2.

Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.

Roboz, Gail J; DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Mims, Alice S; Prince, Gabrielle T; Altman, Jessica K; Arellano, Martha L; Donnellan, Will; Erba, Harry P; Mannis, Gabriel N; Pollyea, Daniel A; Stein, Anthony S; Uy, Geoffrey L; Watts, Justin M; Fathi, Amir T; Kantarjian, Hagop M; Tallman, Martin S; Choe, Sung; Dai, David; Fan, Bin; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Hickman, Denice; Liu, Hua; Agresta, Samuel V; Wu, Bin; Attar, Eyal C; Stone, Richard M.

Blood ; 135(7): 463-471, 2020 02 13.

Artículo en Inglés | MEDLINE | ID: mdl-31841594

3.

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.

DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Roboz, Gail J; Altman, Jessica K; Mims, Alice S; Swords, Ronan; Collins, Robert H; Mannis, Gabriel N; Pollyea, Daniel A; Donnellan, Will; Fathi, Amir T; Pigneux, Arnaud; Erba, Harry P; Prince, Gabrielle T; Stein, Anthony S; Uy, Geoffrey L; Foran, James M; Traer, Elie; Stuart, Robert K; Arellano, Martha L; Slack, James L; Sekeres, Mikkael A; Willekens, Christophe; Choe, Sung; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Yang, Hua; Dai, David; Fan, Bin; Goldwasser, Meredith; Liu, Hua; Agresta, Sam; Wu, Bin; Attar, Eyal C; Tallman, Martin S; Stone, Richard M; Kantarjian, Hagop M.

N Engl J Med ; 378(25): 2386-2398, 2018 Jun 21.

Artículo en Inglés | MEDLINE | ID: mdl-29860938

4.

Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.

Stein, Eytan M; DiNardo, Courtney D; Fathi, Amir T; Pollyea, Daniel A; Stone, Richard M; Altman, Jessica K; Roboz, Gail J; Patel, Manish R; Collins, Robert; Flinn, Ian W; Sekeres, Mikkael A; Stein, Anthony S; Kantarjian, Hagop M; Levine, Ross L; Vyas, Paresh; MacBeth, Kyle J; Tosolini, Alessandra; VanOostendorp, Jason; Xu, Qiang; Gupta, Ira; Lila, Thomas; Risueno, Alberto; Yen, Katharine E; Wu, Bin; Attar, Eyal C; Tallman, Martin S; de Botton, Stéphane.

Blood ; 133(7): 676-687, 2019 02 14.

Artículo en Inglés | MEDLINE | ID: mdl-30510081

5.

A phase I study of lenalidomide plus chemotherapy with mitoxantrone, etoposide, and cytarabine for the reinduction of patients with acute myeloid leukemia.

DeAngelo, Daniel J; Brunner, Andrew M; Werner, Lillian; Avigan, David; Fathi, Amir T; Sperling, Adam S; Washington, Abigail; Stroopinsky, Dina; Rosenblatt, Jacalyn; McMasters, Malgorzata; Luptakova, Katarina; Wadleigh, Martha; Steensma, David P; Hobbs, Gabriela S; Attar, Eyal C; Amrein, Philip C; Ebert, Benjamin L; Stone, Richard M; Ballen, Karen K.

Am J Hematol ; 93(2): 254-261, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29119643

6.

Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia.

Fathi, Amir T; Wander, Seth A; Blonquist, Traci M; Brunner, Andrew M; Amrein, Philip C; Supko, Jeffrey; Hermance, Nicole M; Manning, Amity L; Sadrzadeh, Hossein; Ballen, Karen K; Attar, Eyal C; Graubert, Timothy A; Hobbs, Gabriela; Joseph, Christelle; Perry, Ashley M; Burke, Meghan; Silver, Regina; Foster, Julia; Bergeron, Meghan; Ramos, Aura Y; Som, Tina T; Fishman, Kaitlyn M; McGregor, Kristin L; Connolly, Christine; Neuberg, Donna S; Chen, Yi-Bin.

Haematologica ; 102(4): 719-727, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28034990

7.

Phase 2 study of intensified chemotherapy and allogeneic hematopoietic stem cell transplantation for older patients with acute lymphoblastic leukemia.

Fathi, Amir T; DeAngelo, Daniel J; Stevenson, Kristen E; Kolitz, Jonathan E; Asch, Julie D; Amrein, Philip C; Attar, Eyal C; Steensma, David P; Wadleigh, Martha; Foster, Julia; Connolly, Christine; Galinsky, Ilene; Devoe, Craig E; Stone, Richard M; Neuberg, Donna S; Ballen, Karen K.

Cancer ; 122(15): 2379-88, 2016 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-27171984

8.

Health care utilization and end-of-life care for older patients with acute myeloid leukemia.

El-Jawahri, Areej R; Abel, Gregory A; Steensma, David P; LeBlanc, Thomas W; Fathi, Amir T; Graubert, Timothy A; DeAngelo, Daniel J; Wadleigh, Martha; Ballen, Karen K; Foster, Julia E; Attar, Eyal C; Amrein, Philip C; Brunner, Andrew M; Stone, Richard M; Temel, Jennifer S.

Cancer ; 121(16): 2840-8, 2015 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-25926135

9.

Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy.

Coutre, Steven E; Othus, Megan; Powell, Bayard; Willman, Cheryl L; Stock, Wendy; Paietta, Elisabeth; Levitan, Denise; Wetzler, Meir; Attar, Eyal C; Altman, Jessica K; Gore, Steven D; Maher, Tracy; Kopecky, Kenneth J; Tallman, Martin S; Larson, Richard A; Appelbaum, Frederick R.

Br J Haematol ; 165(4): 497-503, 2014 May.

Artículo en Inglés | MEDLINE | ID: mdl-24528179

10.

Get out--and stay out.

Attar, Eyal C.

Blood ; 119(17): 3869-70, 2012 Apr 26.

Artículo en Inglés | MEDLINE | ID: mdl-22538491

11.

Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response.

Fathi, Amir T; Sadrzadeh, Hossein; Borger, Darrell R; Ballen, Karen K; Amrein, Philip C; Attar, Eyal C; Foster, Julia; Burke, Meghan; Lopez, Hector U; Matulis, Christina R; Edmonds, Katherine M; Iafrate, A John; Straley, Kimberly S; Yen, Katharine E; Agresta, Samuel; Schenkein, David P; Hill, Cedric; Emadi, Ashkan; Neuberg, Donna S; Stone, Richard M; Chen, Yi-Bin.

Blood ; 120(23): 4649-52, 2012 Nov 29.

Artículo en Inglés | MEDLINE | ID: mdl-23074281

12.

Busulfan dose intensity and outcomes in reduced-intensity allogeneic peripheral blood stem cell transplantation for myelodysplastic syndrome or acute myeloid leukemia.

Chen, Yi-Bin; Coughlin, Erin; Kennedy, Kevin F; Alyea, Edwin P; Armand, Philippe; Attar, Eyal C; Ballen, Karen K; Cutler, Corey; Dey, Bimalangshu R; Koreth, John; McAfee, Steven L; Spitzer, Thomas R; Antin, Joseph H; Soiffer, Robert J; Ho, Vincent T.

Biol Blood Marrow Transplant ; 19(6): 981-7, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23562738

13.

Association between baseline body mass index and overall survival among patients over age 60 with acute myeloid leukemia.

Brunner, Andrew M; Sadrzadeh, Hossein; Feng, Yang; Drapkin, Benjamin J; Ballen, Karen K; Attar, Eyal C; Amrein, Philip C; McAfee, Steven L; Chen, Yi-Bin; Neuberg, Donna S; Fathi, Amir T.

Am J Hematol ; 88(8): 642-6, 2013 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-23619915

14.

Eprenetapopt combined with venetoclax and azacitidine in TP53-mutated acute myeloid leukaemia: a phase 1, dose-finding and expansion study.

Garcia-Manero, Guillermo; Goldberg, Aaron D; Winer, Eric S; Altman, Jessica K; Fathi, Amir T; Odenike, Olatoyosi; Roboz, Gail J; Sweet, Kendra; Miller, Crystal; Wennborg, Anders; Hickman, Denice K; Kanagal-Shamanna, Rashmi; Kantarjian, Hagop; Lancet, Jeffrey; Komrokji, Rami; Attar, Eyal C; Sallman, David A.

Lancet Haematol ; 10(4): e272-e283, 2023 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-36990622

15.

Case records of the Massachusetts General Hospital. Case 33-2014. A 60-year-old man with bone pain.

Choy, Edwin; Attar, Eyal C; Oh, Kevin S; Huang, Ambrose J; Kerr, Darcy A.

N Engl J Med ; 371(17): 1630-40, 2014 Oct 23.

Artículo en Inglés | MEDLINE | ID: mdl-25337753

16.

Eprenetapopt Plus Azacitidine After Allogeneic Hematopoietic Stem-Cell Transplantation for TP53-Mutant Acute Myeloid Leukemia and Myelodysplastic Syndromes.

Mishra, Asmita; Tamari, Roni; DeZern, Amy E; Byrne, Michael T; Gooptu, Mahasweta; Chen, Yi-Bin; Deeg, H Joachim; Sallman, David; Gallacher, Phillip; Wennborg, Anders; Hickman, Denice K; Attar, Eyal C; Fernandez, Hugo F.

J Clin Oncol ; 40(34): 3985-3993, 2022 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-35816664

17.

Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes.

Sallman, David A; DeZern, Amy E; Garcia-Manero, Guillermo; Steensma, David P; Roboz, Gail J; Sekeres, Mikkael A; Cluzeau, Thomas; Sweet, Kendra L; McLemore, Amy; McGraw, Kathy L; Puskas, John; Zhang, Ling; Yao, Jiqiang; Mo, Qianxing; Nardelli, Lisa; Al Ali, Najla H; Padron, Eric; Korbel, Greg; Attar, Eyal C; Kantarjian, Hagop M; Lancet, Jeffrey E; Fenaux, Pierre; List, Alan F; Komrokji, Rami S.

J Clin Oncol ; 39(14): 1584-1594, 2021 05 10.

Artículo en Inglés | MEDLINE | ID: mdl-33449813

18.

Donor-derived second hematologic malignancies after cord blood transplantation.

Ballen, Karen K; Cutler, Corey; Yeap, Beow Y; McAfee, Steven L; Dey, Bimalangshu R; Attar, Eyal C; Chen, Yi-Bin; Haspel, Richard L; Liney, Deborah; Koreth, John; Ho, Vincent; Alyea, Edwin P; Soiffer, Robert J; Spitzer, Thomas R; Antin, Joseph H.

Biol Blood Marrow Transplant ; 16(7): 1025-31, 2010 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-20178854

19.

Clinical pharmacokinetics and pharmacodynamics of ivosidenib in patients with advanced hematologic malignancies with an IDH1 mutation.

Fan, Bin; Dai, David; DiNardo, Courtney D; Stein, Eytan; de Botton, Stéphane; Attar, Eyal C; Liu, Hua; Liu, Guowen; Lemieux, Ian; Agresta, Samuel V; Yang, Hua.

Cancer Chemother Pharmacol ; 85(5): 959-968, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32296873

20.

Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial.

Stein, Eytan M; Fathi, Amir T; DiNardo, Courtney D; Pollyea, Daniel A; Roboz, Gail J; Collins, Robert; Sekeres, Mikkael A; Stone, Richard M; Attar, Eyal C; Frattini, Mark G; Tosolini, Alessandra; Xu, Qiang; See, Wendy L; MacBeth, Kyle J; de Botton, Stéphane; Tallman, Martin S; Kantarjian, Hagop M.

Lancet Haematol ; 7(4): e309-e319, 2020 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-32145771

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