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1.
Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based ß-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial.
J Med Chem
; 64(4): 1873-1888, 2021 02 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33588527
2.
Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
J Med Chem
; 58(4): 1760-75, 2015 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25625617
3.
Solution-phase parallel synthesis of carbamates using polymer-bound N-hydroxysuccinimide.
Org Lett
; 4(22): 3923-6, 2002 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-12599493
4.
Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
J Med Chem
; 56(11): 4343-56, 2013 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23634759
5.
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): implications for the binding mode.
Bioorg Med Chem
; 13(17): 5164-70, 2005 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15951185
6.
Structure-based design of a highly selective catalytic site-directed inhibitor of Ser/Thr protein phosphatase 2B (calcineurin).
J Am Chem Soc
; 125(32): 9740-9, 2003 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-12904040
7.
Conversion of Ca2+ salt of an organic compound to its Li+ salt to simplify the fast atom bombardment mass spectrum.
Chem Pharm Bull (Tokyo)
; 51(11): 1341-4, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14600389
8.
Design, synthesis, and structure-activity relationship of new isobenzofuranone ligands of protein kinase C.
Bioorg Med Chem Lett
; 14(11): 2963-7, 2004 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-15125969
9.
Evaluation of series of isobenzofuranone dimers as PKCalpha ligands: implication for the distance between the two ligand binding sites.
Bioorg Med Chem Lett
; 14(11): 2969-72, 2004 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-15125970
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