Detalles de la búsqueda
1.
Repurposing of conformationally-restricted cyclopentane-based AKT-inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine.
Bioorg Chem
; 141: 106890, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37783099
2.
Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits.
Biochem Biophys Res Commun
; 569: 193-198, 2021 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34256188
3.
In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei.
Molecules
; 25(8)2020 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32340370
4.
Identification of Novel Flavonoids and Ansa-Macrolides with Activities against Leishmania donovani through Natural Product Library Screening.
Pathogens
; 13(3)2024 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38535556
5.
Autophagy-regulating small molecules and their therapeutic applications.
Chem Soc Rev
; 41(8): 3245-63, 2012 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22293658
6.
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites.
ACS Infect Dis
; 9(2): 342-364, 2023 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36706233
7.
Fluorescent zinc sensor with minimized proton-induced interferences: photophysical mechanism for fluorescence turn-on response and detection of endogenous free zinc ions.
Inorg Chem
; 51(16): 8760-74, 2012 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-22534151
8.
In Vivo Efficacy of SQ109 against Leishmania donovani, Trypanosoma spp. and Toxoplasma gondii and In Vitro Activity of SQ109 Metabolites.
Biomedicines
; 10(3)2022 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35327472
9.
A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator.
J Am Chem Soc
; 133(50): 20267-76, 2011 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22074182
10.
Msx2 is required for TNF-α-induced canonical Wnt signaling in 3T3-L1 preadipocytes.
Biochem Biophys Res Commun
; 408(3): 399-404, 2011 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21514273
11.
Zn2+-triggered amide tautomerization produces a highly Zn2+-selective, cell-permeable, and ratiometric fluorescent sensor.
J Am Chem Soc
; 132(2): 601-10, 2010 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-20000765
12.
Complete reductive dechlorination of tetrachloroethene to ethene by anaerobic microbial enrichment culture developed from sediment.
Biotechnol Lett
; 32(12): 1829-35, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20714784
13.
Infectivity and Drug Susceptibility Profiling of Different Leishmania-Host Cell Combinations.
Pathogens
; 9(5)2020 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32443883
14.
Monitoring bacterial population dynamics using real-time PCR during the bioremediation of crude-oil-contaminated soil.
J Microbiol Biotechnol
; 19(4): 339-45, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19420987
15.
Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms.
Cell Chem Biol
; 25(10): 1242-1254.e8, 2018 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30057298
16.
Monitoring of microbial diversity and activity during bioremediation of crude oil-contaminated soil with different treatments.
J Microbiol Biotechnol
; 17(1): 67-73, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18051355
17.
A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations.
Nat Chem
; 9(7): 667-675, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28644464
18.
Phytoremediation of soil contaminated with cadmium and/or 2,4,6-trinitrotoluene.
J Environ Biol
; 27(2 Suppl): 311-6, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17436516
19.
EDTA-assisted phytoextraction of lead from lead-contaminated soils by Echinochloa crusgalli var. frumentacea.
J Environ Biol
; 26(1): 151-4, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-16114477
20.
A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens.
Sci Rep
; 5: 17642, 2015 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-26631605