Detalles de la búsqueda
1.
The SLC6A15-SLC6A20 Neutral Amino Acid Transporter Subfamily: Functions, Diseases, and Their Therapeutic Relevance.
Pharmacol Rev
; 76(1): 142-193, 2023 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37940347
2.
New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease.
J Enzyme Inhib Med Chem
; 38(1): 2158822, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36629422
3.
Taurine and Creatine Transporters as Potential Drug Targets in Cancer Therapy.
Int J Mol Sci
; 24(4)2023 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36835201
4.
Analysis of Binding Determinants for Different Classes of Competitive and Noncompetitive Inhibitors of Glycine Transporters.
Int J Mol Sci
; 23(14)2022 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35887394
5.
Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype.
Int J Mol Sci
; 23(15)2022 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955932
6.
Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.
Molecules
; 28(1)2022 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615435
7.
Biological evaluation and molecular docking of novel 1,3,4-thiadiazole-resorcinol conjugates as multifunctional cholinesterases inhibitors.
Bioorg Chem
; 107: 104617, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33444983
8.
Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
Bioorg Chem
; 114: 105129, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34217977
9.
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates.
J Enzyme Inhib Med Chem
; 36(1): 437-449, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33467931
10.
Biphenylalkoxyamine Derivatives-Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.
Molecules
; 26(12)2021 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34208297
11.
Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease.
J Enzyme Inhib Med Chem
; 35(1): 1944-1952, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33092411
12.
New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 21(11)2020 May 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32466601
13.
Synthesis, physicochemical and biological evaluation of tacrine derivative labeled with technetium-99m and gallium-68 as a prospective diagnostic tool for early diagnosis of Alzheimer's disease.
Bioorg Chem
; 91: 103136, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31374521
14.
Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives.
Bioorg Chem
; 90: 103084, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31271942
15.
Identification of 1,2,4-triazoles as new thymidine phosphorylase inhibitors: Future anti-tumor drugs.
Bioorg Chem
; 85: 209-220, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30634096
16.
Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 20(3)2019 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30678364
17.
Determination of ligand efficiency indices in a group of 7H-purine-2,6-dione derivatives with psychotropic activity using micellar electrokinetic chromatography.
Electrophoresis
; 39(19): 2446-2453, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30051931
18.
4-tert-Pentylphenoxyalkyl derivatives - Histamine H3 receptor ligands and monoamine oxidase B inhibitors.
Bioorg Med Chem Lett
; 28(23-24): 3596-3600, 2018 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30404719
19.
Novel carbamate derivatives as selective butyrylcholinesterase inhibitors.
Bioorg Chem
; 78: 29-38, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29529519
20.
Novel pyridine-2,4,6-tricarbohydrazide thiourea compounds as small key organic molecules for the potential treatment of type-2 diabetes mellitus: In vitro studies against yeast α- and ß-glucosidase and in silico molecular modeling.
Arch Pharm (Weinheim)
; 351(1)2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-29194730