Detalles de la búsqueda
1.
BI-Y, an Neuropilin-1 Antagonist, Enhances Revascularization and Prevents Vascular Endothelial Growth Factor-A Induced Retinal Hyperpermeability in Rodent Models of Retinopathies.
J Pharmacol Exp Ther
; 385(3): 214-221, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36997325
2.
Efficacy of an Anti-Semaphorin 3A Neutralizing Antibody in a Male Experimental Retinal Vein Occlusion Mouse Model.
Invest Ophthalmol Vis Sci
; 63(8): 14, 2022 07 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35822950
3.
Characterization and Validation of In Vitro and In Vivo Models to Investigate TNF-α-Induced Inflammation in Retinal Diseases.
Transl Vis Sci Technol
; 11(5): 18, 2022 05 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35579886
4.
Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy.
Transl Vis Sci Technol
; 11(6): 17, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35727188
5.
Transcriptome analysis of AAV-induced retinopathy models expressing human VEGF, TNF-α, and IL-6 in murine eyes.
Sci Rep
; 12(1): 19395, 2022 11 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36371417
6.
Transcriptional comparison of adult human primary Retinal Pigment Epithelium, human pluripotent stem cell-derived Retinal Pigment Epithelium, and ARPE19 cells.
Front Cell Dev Biol
; 10: 910040, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36092714
7.
A structural insight into the reorientation of transmembrane domains 3 and 5 during family A G protein-coupled receptor activation.
Mol Pharmacol
; 79(2): 262-9, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21081645
8.
A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein.
ChemMedChem
; 16(4): 630-639, 2021 02 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33030297
9.
AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice.
Transl Vis Sci Technol
; 10(11): 15, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34520511
10.
Amine oxidase copper-containing 3 (AOC3) inhibition: a potential novel target for the management of diabetic retinopathy.
Int J Retina Vitreous
; 7(1): 30, 2021 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33845913
11.
Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy.
Pharmaceutics
; 13(8)2021 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34452066
12.
In-depth transcriptomic analysis of human retina reveals molecular mechanisms underlying diabetic retinopathy.
Sci Rep
; 11(1): 10494, 2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34006945
13.
Molecular determinants of ligand binding to H4R species variants.
Mol Pharmacol
; 77(5): 734-43, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20103609
14.
Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.
Bioorg Med Chem
; 17(11): 3987-94, 2009 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19414267
15.
Cloning and characterization of dominant negative splice variants of the human histamine H4 receptor.
Biochem J
; 414(1): 121-31, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18452403
16.
Constitutively active mutants of the histamine H1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class A G protein-coupled receptors.
Mol Pharmacol
; 73(1): 94-103, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17959710
17.
Phenylalanine 169 in the second extracellular loop of the human histamine H4 receptor is responsible for the difference in agonist binding between human and mouse H4 receptors.
J Pharmacol Exp Ther
; 327(1): 88-96, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18635748
18.
4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
J Med Chem
; 51(10): 2944-53, 2008 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-18433114
19.
The histamine H3 receptor: from gene cloning to H3 receptor drugs.
Nat Rev Drug Discov
; 4(2): 107-20, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15665857
20.
An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity.
J Pharmacol Exp Ther
; 323(3): 888-98, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17855474