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1.
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress.
Proc Natl Acad Sci U S A
; 112(43): E5834-43, 2015 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26430237
2.
Comparison and functional characterisation of peripheral blood mononuclear cells isolated from filarial lymphoedema and endemic normals of a South Indian population.
Trop Med Int Health
; 22(11): 1414-1427, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28869696
3.
Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain.
J Pharmacol Exp Ther
; 358(3): 371-86, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27411717
4.
Oxazolidinone-based allosteric modulators of mGluR5: Defining molecular switches to create a pharmacological tool box.
Bioorg Med Chem Lett
; 26(17): 4165-9, 2016 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27496211
5.
Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential.
Bioorg Med Chem Lett
; 26(24): 5871-5876, 2016 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27856084
6.
Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase.
J Biol Chem
; 288(30): 21688-702, 2013 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23760263
7.
Identification and characterization of a novel nematode pan allergen (NPA) from Wuchereria bancrofti and their potential role in human filarial tropical pulmonary eosinophilia (TPE).
PLoS Negl Trop Dis
; 18(2): e0011972, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38354188
8.
The frequency and clinical outcome of mono-hit and multi-hit TP53 aberrations in newly diagnosed multiple myeloma.
Pathology
; 56(4): 556-564, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38413253
9.
Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.
Biochemistry
; 52(51): 9375-84, 2013 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24251446
10.
Dose selection for biological enzyme replacement therapy indicated for inborn errors of metabolism.
Clin Transl Sci
; 16(12): 2438-2457, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37735717
11.
Impact of Organ Impairment on the Pharmacokinetics of Therapeutic Peptides and Proteins.
AAPS J
; 25(4): 54, 2023 05 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37231199
12.
Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamate.
Biochemistry
; 51(40): 7940-52, 2012 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-22970650
13.
Solid-state nuclear magnetic resonance studies delineate the role of the protein in activation of both aromatic rings of thiamin.
J Am Chem Soc
; 134(1): 665-72, 2012 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22092024
14.
Determination of pre-steady-state rate constants on the Escherichia coli pyruvate dehydrogenase complex reveals that loop movement controls the rate-limiting step.
J Am Chem Soc
; 134(45): 18644-55, 2012 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23088422
15.
Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.
J Am Chem Soc
; 134(8): 3873-85, 2012 Feb 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-22300533
16.
The success rate of interphase fluorescence in situ hybridization in plasma cell disorders can be improved using unconventional sources of plasma cells.
Int J Lab Hematol
; 44(1): 157-162, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34636141
17.
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.
J Med Chem
; 65(6): 4534-4564, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35261239
18.
Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.
J Med Chem
; 65(6): 4457-4480, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35257579
19.
Assignment of function to histidines 260 and 298 by engineering the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase complex; substitutions that lead to acceptance of substrates lacking the 5-carboxyl group.
Biochemistry
; 50(35): 7705-9, 2011 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-21809826
20.
Whole Genomic analysis of a clinical isolate of Uropathogenic Escherichia coli strain of Sequence Type - 101 carrying the drug resistance NDM-7 in IncX3 plasmid.
Bioinformation
; 17(1): 126-131, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34393427