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1.
Alectinib versus Crizotinib in Untreated ALK-Positive Non-Small-Cell Lung Cancer.
N Engl J Med
; 377(9): 829-838, 2017 08 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-28586279
2.
Mechanism of Action of Inhaled Insulin on Whole Body Glucose Metabolism in Subjects with Type 2 Diabetes Mellitus.
Int J Mol Sci
; 20(17)2019 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-31470605
3.
Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial.
Lancet Oncol
; 17(2): 234-242, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26708155
4.
Assessing the impact of digital patient monitoring on health outcomes and healthcare resource usage in addition to the feasibility of its combination with at-home treatment, in participants receiving systemic anticancer treatment in clinical practice: protocol for an interventional, open-label, multicountry platform study (ORIGAMA).
BMJ Open
; 13(4): e063242, 2023 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37076159
5.
Pharmacometric analyses of alectinib to facilitate approval of the optimal dose for the first-line treatment of anaplastic lymphoma kinase-positive non-small cell lung cancer.
CPT Pharmacometrics Syst Pharmacol
; 10(11): 1357-1370, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34547184
6.
Pooled overall survival and safety data from the pivotal phase II studies (NP28673 and NP28761) of alectinib in ALK-positive non-small-cell lung cancer.
Lung Cancer
; 139: 22-27, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31706099
7.
Patient-reported outcomes from the randomized phase III ALEX study of alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer.
Lung Cancer
; 138: 79-87, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31654838
8.
Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALK-Positive Advanced Non-Small Cell Lung Cancer in the Global Phase III ALEX Study.
J Thorac Oncol
; 14(7): 1233-1243, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30902613
9.
Exposure-response analysis of alectinib in crizotinib-resistant ALK-positive non-small cell lung cancer.
Cancer Chemother Pharmacol
; 82(1): 129-138, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29748847
10.
Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib.
J Clin Pharmacol
; 58(12): 1618-1628, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30052269
11.
Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects.
Clin Pharmacol Drug Dev
; 6(4): 388-397, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27545320
12.
Effect of alectinib on cardiac electrophysiology: results from intensive electrocardiogram monitoring from the pivotal phase II NP28761 and NP28673 studies.
Cancer Chemother Pharmacol
; 79(3): 559-568, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28243683
13.
Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP28673 and NP28761) of Alectinib in ALK-positive Non-Small Cell Lung Cancer.
J Thorac Oncol
; 12(10): 1552-1560, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28689043
14.
Optimized Alectinib Dose Regimen for Treatment of Patients With ALK-Positive Non-Small Cell Lung Cancer Based on Robust Pharmacometric Analyses and Clinical Evidence.
Clin Pharmacol Ther
; 110(5): 1162-1163, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34365647
15.
Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study.
J Clin Oncol
; 34(7): 661-8, 2016 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26598747
16.
The effect of a combined treatment with propranolol and isosorbide-5-mononitrate on Doppler ultrasound parameters in patients with cirrhosis and portal hypertension.
Rom J Gastroenterol
; 14(2): 123-7, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15990930
17.
Examining the safety of PPAR agonists - current trends and future prospects.
Expert Opin Drug Saf
; 12(1): 65-79, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23134541
18.
Allergic skin reaction to insulin detemir: resolution with continued use.
Endocr Pract
; 14(6): 796-7, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18996804
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