Detalles de la búsqueda
1.
Cell Penetrating Peptides Conjugated to Anti-Carcinoembryonic Antigen "Catch-and-Release" Monoclonal Antibodies Alter Plasma and Tissue Pharmacokinetics in Colorectal Cancer Xenograft Mice.
Bioconjug Chem
; 33(8): 1456-1466, 2022 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35867869
2.
Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Prediction of Monoclonal Antibody Tumor Disposition.
Int J Mol Sci
; 23(2)2022 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35054865
3.
Half-Life Extension and Biodistribution Modulation of Biotherapeutics via Red Blood Cell Hitch-Hiking with Novel Anti-Band 3 Single-Domain Antibodies.
Int J Mol Sci
; 24(1)2022 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36613917
4.
The impact of sialylation linkage-type on the pharmacokinetics of recombinant butyrylcholinesterases.
Biotechnol Bioeng
; 117(1): 157-166, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31544955
5.
High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths.
Anal Chem
; 91(5): 3475-3483, 2019 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30712341
6.
Antibody Dependent Enhancement of Acinetobacter baumannii Infection in a Mouse Pneumonia Model.
J Pharmacol Exp Ther
; 368(3): 475-489, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30606761
7.
Sensitive, High-Throughput, and Robust Trapping-Micro-LC-MS Strategy for the Quantification of Biomarkers and Antibody Biotherapeutics.
Anal Chem
; 90(3): 1870-1880, 2018 02 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29276835
8.
"Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer.
J Pharmacol Exp Ther
; 366(1): 205-219, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29735609
9.
Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry.
Mass Spectrom Rev
; 36(6): 734-754, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27097288
10.
The Capsular Polysaccharide of Acinetobacter baumannii Is an Obstacle for Therapeutic Passive Immunization Strategies.
Infect Immun
; 85(12)2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28947651
11.
Physiologically-based pharmacokinetic modeling to predict the clinical pharmacokinetics of monoclonal antibodies.
J Pharmacokinet Pharmacodyn
; 43(4): 427-46, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27377311
12.
Development and validation of an enzyme-linked immunosorbent assay for the quantification of gelonin in mouse plasma.
J Immunoassay Immunochem
; 37(6): 611-22, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27135787
13.
Scale-up of a physiologically-based pharmacokinetic model to predict the disposition of monoclonal antibodies in monkeys.
J Pharmacokinet Pharmacodyn
; 42(5): 527-40, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26364301
14.
Effects of calibration approaches on the accuracy for LC-MS targeted quantification of therapeutic protein.
Anal Chem
; 86(7): 3575-84, 2014 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24611550
15.
Evaluation of near infrared fluorescent labeling of monoclonal antibodies as a tool for tissue distribution.
Drug Metab Dispos
; 42(11): 1906-13, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25209366
16.
Investigation of the influence of nephropathy on monoclonal antibody disposition: a pharmacokinetic study in a mouse model of diabetic nephropathy.
Pharm Res
; 31(5): 1185-93, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24203494
17.
Predicting the effects of 8C2, a monoclonal anti-topotecan antibody, on plasma and tissue disposition of topotecan.
J Pharmacokinet Pharmacodyn
; 41(1): 55-69, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24368689
18.
Investigation of the role of FcγR and FcRn in mAb distribution to the brain.
Mol Pharm
; 10(5): 1505-13, 2013 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22838637
19.
Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies.
J Pharmacokinet Pharmacodyn
; 40(5): 597-607, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23996115
20.
Mechanisms of ADC Toxicity and Strategies to Increase ADC Tolerability.
Cancers (Basel)
; 15(3)2023 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36765668