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1.
The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization.
Bioorg Med Chem
; 29: 115865, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33285410
2.
Design and synthesis of aryl sulfonamide-based nonsteroidal mineralocorticoid receptor antagonists.
Bioorg Med Chem Lett
; 23(23): 6239-42, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24157365
3.
PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy.
Front Pharmacol
; 4: 115, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24133446
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