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1.
Rapid differentiation of nucleotide phosphoramidate diastereomers by electrospray ionization tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 26(16): 1887-92, 2012 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-22777791
2.
ß-D-2'-α-F-2'-ß-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study.
Bioorg Med Chem Lett
; 22(18): 5924-9, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22892115
3.
A liquid chromatography-tandem mass spectrometry method for the quantitative determination of diastereomers of a phosphoramidate nucleotide prodrug (PSI-7851) in human plasma.
Biomed Chromatogr
; 26(5): 583-8, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21842514
4.
Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977.
J Biol Chem
; 285(45): 34337-47, 2010 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-20801890
5.
2'-deoxy-2'-α-fluoro-2'-ß-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.
Bioorg Med Chem Lett
; 20(24): 7376-80, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21050754
6.
Pyrazolopyrimidinones, a novel class of copper-dependent bactericidal antibiotics against multi-drug resistant S. aureus.
Metallomics
; 11(4): 784-798, 2019 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-30855050
7.
Simultaneous determination of rifampicin and levofloxacin concentrations in catheter segments from a mouse model of a device-related infection by liquid chromatography/electrospray ionization tandem mass spectrometry.
J Pharm Biomed Anal
; 46(4): 723-7, 2008 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-18178051
8.
Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation.
ACS Med Chem Lett
; 7(2): 177-81, 2016 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26985294
9.
Determination of tacrine metabolites in microsomal incubate by high performance liquid chromatography-nuclear magnetic resonance/mass spectrometry with a column trapping system.
J Pharm Biomed Anal
; 28(1): 23-30, 2002 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11861105
10.
Discovery of a novel class of potent HCV NS4B inhibitors: SAR studies on piperazinone derivatives.
J Med Chem
; 57(5): 2136-60, 2014 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24476391
11.
Phosphoramidate prodrugs of (-)-ß-D-(2R,4R)-dioxolane-thymine (DOT) as potent anti-HIV agents.
Antivir Chem Chemother
; 22(5): 217-38, 2012 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-22358223
12.
Synthesis of stable isotope labeled analogs of the anti-hepatitis C virus nucleotide prodrugs PSI-7977 and PSI-352938.
Nucleosides Nucleotides Nucleic Acids
; 30(11): 886-96, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22060553
13.
Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV Infection.
ACS Med Chem Lett
; 2(2): 130-5, 2011 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900291
14.
Discovery of a ß-d-2'-deoxy-2'-α-fluoro-2'-ß-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus.
J Med Chem
; 53(19): 7202-18, 2010 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20845908
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