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1.
The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity.
Biochem Biophys Res Commun
; 716: 150011, 2024 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38704890
2.
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers.
Invest New Drugs
; 39(5): 1213-1221, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33710464
3.
Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy.
Biochem Pharmacol
; 222: 116071, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38387527
4.
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy.
Biochem Pharmacol
; 223: 116198, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38588830
5.
Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells.
Life Sci
; 332: 122129, 2023 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37769804
6.
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance.
EMBO Mol Med
; 15(3): e16235, 2023 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36652375
7.
TNKS inhibitors potentiate proliferative inhibition of BET inhibitors via reducing ß-Catenin in colorectal cancer cells.
Am J Cancer Res
; 12(3): 1069-1087, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35411247
8.
SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy.
Neoplasia
; 32: 100823, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35907292
9.
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1.
Biochem Pharmacol
; 185: 114435, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33539817
10.
Glycogen synthase kinase 3ß inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer.
Cell Death Dis
; 12(2): 183, 2021 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33589588
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