Detalles de la búsqueda
1.
Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
Proc Natl Acad Sci U S A
; 117(29): 17296-17307, 2020 07 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32631998
2.
Development of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease.
Bioorg Med Chem Lett
; 29(7): 929-932, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30773432
3.
Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-ß burden in several amyloid transgenic mouse models.
Glia
; 66(3): 492-504, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29134678
4.
NF-L in cerebrospinal fluid and serum is a biomarker of neuronal damage in an inducible mouse model of neurodegeneration.
Neurobiol Dis
; 104: 73-84, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28392472
5.
Flexibility as a marker of early cognitive decline in humanized apolipoprotein E ε4 (ApoE4) mice.
Neurobiol Aging
; 102: 129-138, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33765426
6.
Validation of memory assessment in the Starmaze task: Data from 14 month-old APPPS1 mice and controls.
Data Brief
; 37: 107266, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34381853
7.
Modifications of physical and functional integrity of the blood-brain barrier in an inducible mouse model of neurodegeneration.
Neuropharmacology
; 191: 108588, 2021 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33940010
8.
Data on synthesis, ADME and pharmacological properties and early safety pharmacology evaluation of a series of novel NURR1/NOT agonist potentially useful for the treatment of Parkinson's disease.
Data Brief
; 27: 104057, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31687426
9.
Gene delivery of a modified antibody to Aß reduces progression of murine Alzheimer's disease.
PLoS One
; 14(12): e0226245, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31887144
10.
High brain distribution of a new central nervous system drug candidate despite its P-glycoprotein-mediated efflux at the mouse blood-brain barrier.
Eur J Pharm Sci
; 117: 68-79, 2018 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29427702
11.
SAR228810: an antibody for protofibrillar amyloid ß peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA).
Alzheimers Res Ther
; 10(1): 117, 2018 11 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30486882
12.
SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy.
Alzheimers Dement (N Y)
; 2(4): 267-280, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-29067314
13.
A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).
PLoS One
; 10(3): e0121072, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25815475
Resultados
1 -
13
de 13
1
Próxima >
>>