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1.
The discovery of tetrahydro-beta-carbolines as inhibitors of the kinesin Eg5.
Bioorg Med Chem Lett
; 20(1): 157-60, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19945875
2.
Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic.
J Med Chem
; 63(5): 2013-2027, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31059256
3.
Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
Nat Commun
; 10(1): 1402, 2019 03 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-30926793
4.
Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.
J Med Chem
; 60(12): 4869-4881, 2017 06 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28557458
5.
Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors.
ACS Med Chem Lett
; 6(1): 37-41, 2015 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-25589927
6.
Structure-Based Drug Design of Novel, Potent, and Selective Azabenzimidazoles (ABI) as ATR Inhibitors.
ACS Med Chem Lett
; 6(1): 42-6, 2015 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-25589928
7.
Enantioselective Ring Opening of Epoxides with Silicon Tetrachloride in the Presence of a Chiral Lewis Base.
J Org Chem
; 63(8): 2428-2429, 1998 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-11672098
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