Detalles de la búsqueda
1.
A phase 1 study in healthy participants to characterize the safety and pharmacology of inclacumab, a fully human anti-P-selectin antibody, in development for treatment of sickle cell disease.
Eur J Clin Pharmacol
; 79(9): 1219-1228, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37436495
2.
Dose Selection for Phase III Clinical Evaluation of Gepotidacin (GSK2140944) in the Treatment of Uncomplicated Urinary Tract Infections.
Antimicrob Agents Chemother
; 66(3): e0149221, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34978887
3.
Pharmacokinetics of Oral Formulations of Gepotidacin (GSK2140944), a Triazaacenaphthylene Bacterial Type II Topoisomerase Inhibitor, in Healthy Adult and Adolescent Participants.
Antimicrob Agents Chemother
; 66(1): e0126321, 2022 01 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34633853
4.
Comparison between physiologically based pharmacokinetic and population pharmacokinetic modelling to select paediatric doses of gepotidacin in plague.
Br J Clin Pharmacol
; 88(2): 416-428, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34289143
5.
Phase 2a Pharmacokinetic, Safety, and Exploratory Efficacy Evaluation of Oral Gepotidacin (GSK2140944) in Female Participants with Uncomplicated Urinary Tract Infection (Acute Uncomplicated Cystitis).
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32284384
6.
Cavitary penetration of levofloxacin among patients with multidrug-resistant tuberculosis.
Antimicrob Agents Chemother
; 59(6): 3149-55, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25779583
7.
Artificial Intelligence: From Buzzword to Useful Tool in Clinical Pharmacology.
Clin Pharmacol Ther
; 115(4): 698-709, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37881133
8.
Clinical assessment of gepotidacin (GSK2140944) as a victim and perpetrator of drug-drug interactions via CYP3A metabolism and transporters.
Clin Transl Sci
; 16(4): 647-661, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36642822
9.
Pharmacokinetic, Safety, and Tolerability Evaluations of Gepotidacin (GSK2140944) in Healthy Japanese Participants.
Clin Pharmacol Drug Dev
; 12(1): 38-56, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36468634
10.
Design and Measurement of Drug Tissue Concentration Asymmetry and Tissue Exposure-Effect (Tissue PK-PD) Evaluation.
J Med Chem
; 65(13): 8713-8734, 2022 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35790118
11.
A simple and rapid method to assess butenafine hydrochloride in skin samples and a comparative cutaneous retention study of two marketed formulations.
Biomed Chromatogr
; 25(10): 1132-7, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21337350
12.
Pharmacokinetics of Gepotidacin in Subjects With Normal Hepatic Function and Hepatic Impairment.
Clin Pharmacol Drug Dev
; 10(6): 588-597, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33450142
13.
Population Pharmacokinetic/Pharmacodynamic Analysis of Intravenous Zanamivir in Healthy Adults and Hospitalized Adult and Pediatric Subjects With Influenza.
Clin Transl Sci
; 13(1): 157-168, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31664778
14.
Population pharmacokinetics of orally administrated bromopride: Focus on the absorption process.
Eur J Pharm Sci
; 142: 105081, 2020 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31669384
15.
Establishment of intracellular tenofovir-diphosphate as the key determinant for in vitro-in vivo translation of antiviral efficacy.
Antiviral Res
; 151: 1-3, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29337165
16.
Simultaneous liquid chromatography- tandem mass spectrometry method to quantify epicatechin and procyanidin B2 in rat plasma after oral administration of Trichilia catigua (catuaba) extract and its application to a pharmacokinetic study
Rev. bras. farmacogn
; 29(4): 457-463, July-Aug. 2019. tab, graf
Artículo
en Inglés
| LILACS | ID: biblio-1042282
17.
Population pharmacokinetics and its role in anti-tuberculosis drug development and optimization of treatment.
Curr Pharm Des
; 17(27): 2889-99, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21834766
18.
Gemifloxacin mesylate (GFM) stability evaluation applying a validated bioassay method and in vitro cytotoxic study.
Talanta
; 83(5): 1774-9, 2011 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21238783
19.
Stability-indicating LC assay for butenafine hydrochloride in creams using an experimental design for robustness evaluation and photodegradation kinetics study.
J Chromatogr Sci
; 49(7): 512-8, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21801482
Resultados
1 -
19
de 19
1
Próxima >
>>