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1.
Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands.
Int J Mol Sci
; 24(7)2023 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37047338
2.
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.
J Biol Chem
; 296: 100795, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34019876
3.
Known Drugs Identified by Structure-Based Virtual Screening Are Able to Bind Sigma-1 Receptor and Increase Growth of Huntington Disease Patient-Derived Cells.
Int J Mol Sci
; 22(3)2021 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33525510
4.
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism.
Amino Acids
; 52(2): 247-259, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31037461
5.
Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases.
Molecules
; 25(8)2020 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32326257
6.
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors.
Mol Pharm
; 15(8): 3069-3078, 2018 08 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29897765
7.
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach.
ACS Infect Dis
; 8(8): 1687-1699, 2022 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35880849
8.
Structural basis of ubiquitination mediated by protein splicing in early Eukarya.
Biochim Biophys Acta Gen Subj
; 1865(5): 129844, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33444728
9.
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome.
Biochim Biophys Acta Gen Subj
; 1864(8): 129618, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32305337
10.
Roles of Sorcin in Drug Resistance in Cancer: One Protein, Many Mechanisms, for a Novel Potential Anticancer Drug Target.
Cancers (Basel)
; 12(4)2020 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32268494
11.
Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme.
PLoS Negl Trop Dis
; 14(5): e0008339, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32437349
12.
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.
Cell Death Dis
; 11(10): 861, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33060591
13.
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase.
Eur J Med Chem
; 152: 527-541, 2018 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29758517
14.
The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket.
J Inorg Biochem
; 169: 86-96, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28161681
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