Detalles de la búsqueda
1.
Regional conformational flexibility couples substrate specificity and scissile phosphate diester selectivity in human flap endonuclease 1.
Nucleic Acids Res
; 46(11): 5618-5633, 2018 06 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29718417
2.
Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins.
Nucleic Acids Res
; 45(21): 12577-12584, 2017 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29045748
3.
α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction.
Proc Natl Acad Sci U S A
; 111(34): 12384-9, 2014 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25104750
4.
Near attack conformers dominate ß-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate.
Proc Natl Acad Sci U S A
; 109(18): 6910-5, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22505741
5.
Close identity between alternatively folded state N2 of ubiquitin and the conformation of the protein bound to the ubiquitin-activating enzyme.
Biochemistry
; 53(3): 447-9, 2014 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24401037
6.
Solution structure of the Q41N variant of ubiquitin as a model for the alternatively folded N2 state of ubiquitin.
Biochemistry
; 52(11): 1874-85, 2013 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-23421577
7.
Fast protein motions are coupled to enzyme H-transfer reactions.
J Am Chem Soc
; 135(7): 2512-7, 2013 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23373704
8.
Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proc Natl Acad Sci U S A
; 107(10): 4555-60, 2010 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20164409
9.
1H, 13C, and 15N resonance assignments of a conserved putative cell wall binding domain from Enterococcus faecalis.
Biomol NMR Assign
; 16(2): 247-251, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35665899
10.
An Enzyme with High Catalytic Proficiency Utilizes Distal Site Substrate Binding Energy to Stabilize the Closed State but at the Expense of Substrate Inhibition.
ACS Catal
; 12(5): 3149-3164, 2022 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35692864
11.
Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.
J Am Chem Soc
; 133(11): 3989-94, 2011 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-21348513
12.
Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.
J Am Chem Soc
; 132(18): 6507-16, 2010 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-20397725
13.
Allomorphy as a mechanism of post-translational control of enzyme activity.
Nat Commun
; 11(1): 5538, 2020 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33139716
14.
Kinetic analysis of beta-phosphoglucomutase and its inhibition by magnesium fluoride.
J Am Chem Soc
; 131(4): 1575-88, 2009 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19132841
15.
MgF(3)(-) and alpha-galactose 1-phosphate in the active site of beta-phosphoglucomutase form a transition state analogue of phosphoryl transfer.
J Am Chem Soc
; 131(45): 16334-5, 2009 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-19852484
16.
Paramagnetic relaxation enhancement-assisted structural characterization of a partially disordered conformation of ubiquitin.
Protein Sci
; 28(11): 1993-2003, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31587403
17.
1H, 15N and 13C backbone resonance assignments of the P146A variant of ß-phosphoglucomutase from Lactococcus lactis in its substrate-free form.
Biomol NMR Assign
; 13(2): 349-356, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31396843
18.
Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase.
ACS Catal
; 9(5): 4394-4401, 2019 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31080692
19.
Conformational exchange in the potassium channel blocker ShK.
Sci Rep
; 9(1): 19307, 2019 12 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-31848433
20.
Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.
J Am Chem Soc
; 130(12): 3952-8, 2008 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-18318536