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1.
An open label trial of nemiralisib, an inhaled PI3 kinase delta inhibitor for the treatment of Activated PI3 kinase Delta Syndrome.
Pulm Pharmacol Ther
; 79: 102201, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36841351
2.
Dominant effect of gap junction communication in wound-induced calcium-wave, NFAT activation and wound closure in keratinocytes.
J Cell Physiol
; 236(12): 8171-8183, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34180060
3.
Bronchial Epithelial Calcium Metabolism Impairment in Smokers and Chronic Obstructive Pulmonary Disease. Decreased ORAI3 Signaling.
Am J Respir Cell Mol Biol
; 61(4): 501-511, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30943377
4.
Use of autologous 99mTechnetium-labelled neutrophils to quantify lung neutrophil clearance in COPD.
Thorax
; 74(7): 659-666, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30674586
5.
Translation of Inhaled Drug Optimization Strategies into Clinical Pharmacokinetics and Pharmacodynamics Using GSK2292767A, a Novel Inhaled Phosphoinositide 3-Kinase δ Inhibitor.
J Pharmacol Exp Ther
; 369(3): 443-453, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30940692
6.
A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Crossover Study To Investigate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Repeat Doses of Inhaled Nemiralisib in Adults with Persistent, Uncontrolled Asthma.
J Pharmacol Exp Ther
; 367(3): 405-413, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30217958
7.
Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition.
Am J Respir Crit Care Med
; 194(8): 961-973, 2016 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27064380
8.
Epithelial-mesenchymal transition, IP3 receptors and ER-PM junctions: translocation of Ca2+ signalling complexes and regulation of migration.
Biochem J
; 473(6): 757-67, 2016 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26759379
9.
Genome-wide transcription profiling in neutrophils in acute respiratory distress syndrome.
Lancet
; 385 Suppl 1: S55, 2015 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-26312877
10.
Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models.
Gastroenterology
; 149(2): 481-92.e7, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25917787
11.
The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells.
Biochem J
; 465(3): 405-12, 2015 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25370603
12.
Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy.
Proc Natl Acad Sci U S A
; 110(32): 13186-91, 2013 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-23878235
13.
Store-Operated Ca2+ Channels in Mesangial Cells Inhibit Matrix Protein Expression.
J Am Soc Nephrol
; 26(11): 2691-702, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25788524
14.
The role of CRAC channel in asthma.
Pulm Pharmacol Ther
; 35: 67-74, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26344428
15.
Reply to: Altered Calcium in Ciliary Dysfunction: Potential Role of ER Stress and Ciliophagy.
Am J Respir Cell Mol Biol
; 61(6): 795-796, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31774332
16.
High glucose and diabetes enhanced store-operated Ca(2+) entry and increased expression of its signaling proteins in mesangial cells.
Am J Physiol Renal Physiol
; 306(9): F1069-80, 2014 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24623143
17.
CRAC channel inhibition produces greater anti-inflammatory effects than glucocorticoids in CD8 cells from COPD patients.
Clin Sci (Lond)
; 126(3): 223-32, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23905758
18.
Lead identification of benzimidazolone and azabenzimidazolone arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists.
Bioorg Med Chem
; 22(15): 4298-311, 2014 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24909677
19.
CRACM/Orai ion channel expression and function in human lung mast cells.
J Allergy Clin Immunol
; 129(6): 1628-35.e2, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22409987
20.
Divergent age-related humoral correlates of protection against respiratory syncytial virus infection in older and young adults: a pilot, controlled, human infection challenge model.
Lancet Healthy Longev
; 3(6): e405-e416, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36098319