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1.
Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.
PLoS Pathog
; 14(2): e1006889, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29425244
2.
Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans.
J Antimicrob Chemother
; 74(2): 442-452, 2019 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30376079
3.
Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study.
N Engl J Med
; 373(21): 2048-58, 2015 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-26580997
4.
Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.
PLoS Pathog
; 11(6): e1004995, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-26098424
5.
Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2'-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases.
Antimicrob Agents Chemother
; 59(12): 7504-16, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26392512
6.
Efficiency of incorporation and chain termination determines the inhibition potency of 2'-modified nucleotide analogs against hepatitis C virus polymerase.
Antimicrob Agents Chemother
; 58(7): 3636-45, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24733478
7.
Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group.
Org Biomol Chem
; 8(9): 2131-41, 2010 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-20401390
8.
Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase.
ACS Chem Biol
; 12(1): 83-91, 2017 01 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28103684
9.
Structure-activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs.
Antiviral Res
; 143: 151-161, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28412183
10.
Biochemical Effect of Resistance Mutations against Synergistic Inhibitors of RSV RNA Polymerase.
PLoS One
; 11(5): e0154097, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27163448
11.
Steric interference modification of the hammerhead ribozyme.
Chem Biol
; 9(9): 1009-16, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12323375
12.
Discovery of 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine (ALS-8176), a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection.
J Med Chem
; 58(4): 1862-78, 2015 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25667954
13.
Inhibition of viral RNA polymerases by nucleoside and nucleotide analogs: therapeutic applications against positive-strand RNA viruses beyond hepatitis C virus.
Curr Opin Virol
; 9: 1-7, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25194816
14.
The development of a monoclonal antibody specific for a 2(')-C-allyl modification of uridine, and its use in the localization of ribozymes in vivo.
Anal Biochem
; 307(1): 40-6, 2002 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12137777
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