Detalles de la búsqueda
1.
Symbiotic Antidiabetic Effect of Lactobacillus casei and the Bioactive Extract of Cleome droserifolia (Forssk.) Del. on Mice with Type 2 Diabetes Induced by Alloxan.
Chem Biodivers
; 21(1): e202301397, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38078801
2.
Microwave-assisted synthesis, spectroscopic characterization, and biological evaluation of fused thieno[2,3-d]pyrimidines as potential anti-cancer agents targeting EGFRWT and EGFRT790M.
Mol Divers
; 27(2): 901-917, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35780205
3.
Apoptotic and anti-angiogenic effects of propolis against human bladder cancer: molecular docking and in vitro screening.
Biomarkers
; 27(2): 138-150, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-34927500
4.
Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies.
Bioorg Chem
; 127: 105995, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35792315
5.
Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M.
J Enzyme Inhib Med Chem
; 37(1): 1196-1211, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35470756
6.
Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 1884-1902, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35801486
7.
Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents.
J Enzyme Inhib Med Chem
; 37(1): 2765-2785, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36210545
8.
Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in silico studies.
J Enzyme Inhib Med Chem
; 37(1): 2489-2511, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36093880
9.
Anticoagulants as Potential SARS-CoV-2 Mpro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies.
Int J Mol Sci
; 23(20)2022 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36293094
10.
Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management.
Molecules
; 27(11)2022 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35684529
11.
Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives.
Molecules
; 27(7)2022 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35408463
12.
Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations.
Molecules
; 27(17)2022 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36080338
13.
Identification of Some Promising Heterocycles Useful in Treatment of Allergic Rhinitis: Virtual Screening, Pharmacophore Mapping, Molecular Docking, and Molecular Dynamics.
Russ J Bioorg Chem
; 48(2): 438-456, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35637779
14.
Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR.
Bioorg Chem
; 110: 104794, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33735711
15.
Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma.
Bioorg Chem
; 107: 104532, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33334586
16.
Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFRWT and EGFRT790M.
Org Biomol Chem
; 18(38): 7608-7634, 2020 10 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32959865
17.
Design, synthesis, antimicrobial activity and molecular docking studies of some novel di-substituted sulfonylquinoxaline derivatives.
Bioorg Chem
; 104: 104164, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32896807
18.
Design, synthesis, molecular docking and antiproliferative activity of some novel benzothiazole derivatives targeting EGFR/HER2 and TS.
Bioorg Chem
; 101: 103976, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32506018
19.
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.
Bioorg Chem
; 103: 104233, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32882440
20.
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers.
Bioorg Chem
; 94: 103422, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31812261