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1.
Advancing personalized medicine in neurodegenerative diseases: The role of epigenetics and pharmacoepigenomics in pharmacotherapy.
Pharmacol Res
; 205: 107247, 2024 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38834164
2.
Deletion of Gadd45a Expression in Mice Leads to Cognitive and Synaptic Impairment Associated with Alzheimer's Disease Hallmarks.
Int J Mol Sci
; 25(5)2024 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38473843
3.
Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease.
Neurobiol Dis
; 152: 105278, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33516872
4.
Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics.
CNS Neurosci Ther
; 30(4): e14511, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37905690
5.
Neuroprotective effects of G9a inhibition through modulation of peroxisome-proliferator activator receptor gamma-dependent pathways by miR-128.
Neural Regen Res
; 19(11): 2532-2542, 2024 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38526289
6.
Nutritional, molecular, and functional properties of a novel enzymatically hydrolyzed porcine plasma product.
PLoS One
; 19(5): e0301504, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38728303
7.
G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease.
Aging Dis
; 15(1): 311-337, 2024 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37307824
8.
Repurposing of Raltitrexed as an Effective G9a/EHMT2 Inhibitor and Promising Anti-Alzheimer's Agent.
ACS Med Chem Lett
; 14(11): 1531-1536, 2023 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37974951
9.
A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer's Disease Mice Models.
Pharmaceuticals (Basel)
; 15(8)2022 Jul 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35893732
10.
Structure-Based Virtual Screening and inâ vitro and inâ vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti-Alzheimer's Agents.
ChemMedChem
; 17(13): e202200002, 2022 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35413149
11.
Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice.
Cells
; 11(16)2022 08 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36010679
12.
The Contribution of Epigenetic Inheritance Processes on Age-Related Cognitive Decline and Alzheimer's Disease.
Epigenomes
; 5(2)2021 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34968302
13.
RNA-seq and miRNA-seq data from pharmacological inhibition of the G9a/GLP histone methyltransferase complex with UNC0642 in SAMP8 mice.
Data Brief
; 36: 107114, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-34307805
14.
Synergistic Neuroprotective Effects of a Natural Product Mixture against AD Hallmarks and Cognitive Decline in Caenorhabditis elegans and an SAMP8 Mice Model.
Nutrients
; 13(7)2021 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34371921
15.
The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy.
Ageing Res Rev
; 67: 101271, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33571701
16.
A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice.
Pharmaceutics
; 12(3)2020 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-32235699
17.
Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and ß-Amyloid plaques in an early-onset Alzheimer's disease mouse model.
Aging (Albany NY)
; 11(23): 11591-11608, 2019 12 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31804189
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