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1.
Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity.
Cancer Immunol Immunother
; 72(5): 1327-1335, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-36394642
2.
Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment.
Cancer Immunol Immunother
; 70(8): 2401-2410, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33511454
3.
Antibody-mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo.
Int J Cancer
; 139(6): 1340-9, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27170265
4.
Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers.
Nat Cancer
; 5(1): 66-84, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38151625
5.
Liver Metastasis Modulate Responses of Suppressive Macrophages and Exhausted T Cells to Immunotherapy Revealed by Single Cell Sequencing.
Adv Genet (Hoboken)
; 3(4): 2200002, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36911291
6.
Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe.
J Med Chem
; 65(6): 4972-4990, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35286090
7.
Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Sci Transl Med
; 13(608)2021 08 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34433637
8.
Broad antitumor activity in breast cancer xenografts by motesanib, a highly selective, oral inhibitor of vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors.
Clin Cancer Res
; 15(1): 110-8, 2009 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19118038
9.
Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.
J Med Chem
; 62(22): 10258-10271, 2019 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31736296
10.
AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
Cancer Discov
; 8(12): 1582-1597, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30254093
11.
Local Delivery of OncoVEXmGM-CSF Generates Systemic Antitumor Immune Responses Enhanced by Cytotoxic T-Lymphocyte-Associated Protein Blockade.
Clin Cancer Res
; 23(20): 6190-6202, 2017 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28706012
12.
Ganitumab (AMG 479) inhibits IGF-II-dependent ovarian cancer growth and potentiates platinum-based chemotherapy.
Clin Cancer Res
; 20(11): 2947-58, 2014 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24727326
13.
Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth.
Mol Cancer Ther
; 9(8): 2399-410, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20663930
14.
Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor.
Mol Cancer Ther
; 8(6): 1536-46, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19509246
15.
AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells.
Mol Cancer Ther
; 8(5): 1095-105, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19366899
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