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1.
The Proof-of-Concept of MBA121, a Tacrine-Ferulic Acid Hybrid, for Alzheimer's Disease Therapy.
Int J Mol Sci
; 24(15)2023 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37569630
2.
Synthesis, antioxidant and Aß anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction.
Bioorg Chem
; 85: 221-228, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30640071
3.
Base-Mediated Generation of Ketenimines from Ynamides: Direct Access to Azetidinimines by an Imino-Staudinger Synthesis.
Chemistry
; 23(53): 12991-12994, 2017 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-28627803
4.
Bone metastasis from malignant phyllodes breast tumor: report of two cases.
BMC Clin Pathol
; 16: 4, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26933383
5.
Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.
Molecules
; 21(5)2016 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27187348
6.
New contributions to the drug profile of TNFα inhibitor SPD304: Affinity, selectivity and ADMET considerations.
Eur J Pharmacol
; 907: 174285, 2021 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34181962
7.
Azetidinimines as a novel series of non-covalent broad-spectrum inhibitors of ß-lactamases with submicromolar activities against carbapenemases KPC-2 (class A), NDM-1 (class B) and OXA-48 (class D).
Eur J Med Chem
; 219: 113418, 2021 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33862516
8.
Multitarget Therapeutic Strategies for Alzheimer's Disease: Review on Emerging Target Combinations.
Biomed Res Int
; 2020: 5120230, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32714977
9.
Subtype Selective γ-Aminobutyric Acid Type A Receptor (GABAAR) Modulators Acting at the Benzodiazepine Binding Site: An Update.
J Med Chem
; 63(7): 3425-3446, 2020 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31738537
10.
Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1.
Eur J Med Chem
; 201: 112337, 2020 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32659605
11.
Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer's Disease Therapy.
Curr Alzheimer Res
; 16(9): 815-820, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31660831
12.
A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.
Eur J Med Chem
; 143: 473-490, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29202409
13.
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease.
Prog Neurobiol
; 151: 4-34, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26797191
14.
Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aß1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy.
ChemMedChem
; 11(12): 1318-27, 2016 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26804623
15.
The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.
J Med Chem
; 59(21): 9967-9973, 2016 11 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27736061
16.
Donepezil-ferulic acid hybrids as anti-Alzheimer drugs.
Future Med Chem
; 7(1): 15-21, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25582330
17.
Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
ChemMedChem
; 10(3): 523-39, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25537267
18.
Multitarget-directed ligands for neurodegenerative diseases: real opportunity or blurry mirage?
Future Med Chem
; 11(4): 261-263, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30763133
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