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1.
LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial.
Lancet
; 400(10366): 1869-1881, 2022 11 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-36354040
2.
Cardiac Safety Research Consortium: can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward.
Am Heart J
; 168(3): 262-72, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25173536
3.
Effect of Food Consumption on the Pharmacokinetics, Safety, and Tolerability of Once-Daily Orally Administered Orforglipron (LY3502970), a Non-peptide GLP-1 Receptor Agonist.
Diabetes Ther
; 15(4): 819-832, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38402332
4.
Effects of Hepatic Impairment on the Pharmacokinetics of the Dual GIP and GLP-1 Receptor Agonist Tirzepatide.
Clin Pharmacokinet
; 61(7): 1057-1067, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35674880
5.
Pharmacokinetics and Pharmacodynamics of Human Regular U-500 Insulin Administered via Continuous Subcutaneous Insulin Infusion Versus Subcutaneous Injection in Adults With Type 2 Diabetes and High-Dose Insulin Requirements.
J Diabetes Sci Technol
; 16(2): 401-407, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33242998
6.
Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective.
Clin Pharmacol Ther
; 109(2): 310-318, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32866317
7.
Shared Learnings on the New EMA First-in-Human and Early Clinical Trial Guideline: Proceedings From a DIAlogue Session at DIA Europe 2018.
Ther Innov Regul Sci
; 54(2): 462-467, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32072587
8.
LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.
Mol Metab
; 18: 3-14, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30473097
9.
A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density.
J Bone Miner Res
; 30(2): 216-24, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25196993
10.
The Effect of Discontinuing Treatment With Blosozumab: Follow-up Results of a Phase 2 Randomized Clinical Trial in Postmenopausal Women With Low Bone Mineral Density.
J Bone Miner Res
; 30(9): 1717-25, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25707611
11.
Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial.
Lancet Diabetes Endocrinol
; 3(12): 948-57, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26516121
12.
Teriparatide has no effect on the calcium-mediated pharmacodynamics of digoxin.
Clin Pharmacol Ther
; 73(1): 87-94, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12545147
13.
Mathematical model formulation and validation of water and solute transport in whole hamster pancreatic islets.
Math Biosci
; 254: 64-75, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24950195
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