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1.
Viral clearance, pharmacokinetics and tolerability of ensovibep in patients with mild to moderate COVID-19: A phase 2a, open-label, single-dose escalation study.
Br J Clin Pharmacol
; 89(3): 1105-1114, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36214216
2.
First-in-human trial to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of STR-324, a dual enkephalinase inhibitor for pain management.
Br J Clin Pharmacol
; 88(1): 103-114, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34046921
3.
Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement.
Br J Clin Pharmacol
; 87(12): 4658-4669, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33931884
4.
MicroRNA-122 can be measured in capillary blood which facilitates point-of-care testing for drug-induced liver injury.
Br J Clin Pharmacol
; 83(9): 2027-2033, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28257154
5.
A novel sustained-release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers.
Pharmacol Res Perspect
; 9(2): e00739, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33764642
6.
Validation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study.
Eur J Pharmacol
; 815: 290-297, 2017 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28943100
7.
Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model.
Toxicol Sci
; 159(2): 380-391, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28962522
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