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1.
Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers.
J Pharmacol Exp Ther
; 386(2): 129-137, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37316329
2.
Population pharmacokinetics of clonazepam in saliva and plasma: Steps towards noninvasive pharmacokinetic studies in vulnerable populations.
Br J Clin Pharmacol
; 88(5): 2236-2245, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34811788
3.
Theoretical Performance of Nonlinear Mixed-Effect Models Incorporating Saliva as an Alternative Sampling Matrix for Therapeutic Drug Monitoring in Pediatrics: A Simulation Study.
Ther Drug Monit
; 43(4): 546-554, 2021 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34250966
4.
Population pharmacokinetics and pharmacodynamics of a novel vascular adhesion protein-1 inhibitor using a multiple-target mediated drug disposition model.
J Pharmacokinet Pharmacodyn
; 48(1): 39-53, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32930923
5.
Mechanism-based modeling of the effect of a novel inhibitor of vascular adhesion protein-1 on albuminuria and renal function markers in patients with diabetic kidney disease.
J Pharmacokinet Pharmacodyn
; 48(1): 21-38, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32929612
6.
Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery-Åsberg Depression Rating Scale.
CPT Pharmacometrics Syst Pharmacol
; 12(10): 1425-1436, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37551774
7.
OX40L Inhibition Suppresses KLH-driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof-of-Pharmacology for KY1005.
Clin Pharmacol Ther
; 111(5): 1121-1132, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35092305
8.
A novel sustained-release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers.
Pharmacol Res Perspect
; 9(2): e00739, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33764642
9.
First Clinical Study with AP30663 - a KCa 2 Channel Inhibitor in Development for Conversion of Atrial Fibrillation.
Clin Transl Sci
; 13(6): 1336-1344, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32725783
10.
Safety, pharmacokinetics, and pharmacodynamics of Gln-1062, a prodrug of galantamine.
Alzheimers Dement (N Y)
; 6(1): e12093, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33083515
11.
Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM).
FEMS Microbiol Lett
; 324(1): 28-37, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22092761
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