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1.
An extra virgin olive oil-enriched chocolate spread positively modulates insulin-resistance markers compared with a palm oil-enriched one in healthy young adults: A double-blind, cross-over, randomised controlled trial.
Diabetes Metab Res Rev
; 38(2): e3492, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34435429
2.
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification.
Anal Chem
; 88(19): 9510-9517, 2016 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27583774
3.
Tezacaftor is a direct inhibitor of sphingolipid delta-4 desaturase enzyme (DEGS).
J Cyst Fibros
; 2024 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38789319
4.
Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer.
J Med Chem
; 66(8): 5981-6001, 2023 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37026468
5.
Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance.
J Med Chem
; 65(13): 8998-9010, 2022 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35771181
6.
Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Cell Rep
; 39(1): 110641, 2022 04 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35385746
7.
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach.
J Med Chem
; 64(23): 17277-17286, 2021 12 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34846885
8.
Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome.
J Med Chem
; 64(14): 10203-10229, 2021 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34137257
9.
Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration.
J Med Chem
; 64(18): 13327-13355, 2021 09 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-34469137
10.
Modulation of Efficient Diiodo-BODIPY in vitro Phototoxicity to Cancer Cells by Carbon Nano-Onions.
Front Chem
; 8: 573211, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33134274
11.
Distinctive lipid signatures of bronchial epithelial cells associated with cystic fibrosis drugs, including Trikafta.
JCI Insight
; 5(16)2020 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32673287
12.
Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
J Med Chem
; 63(7): 3508-3521, 2020 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32196342
13.
Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over ß.
J Med Chem
; 63(21): 12873-12886, 2020 11 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33079544
14.
Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors.
J Med Chem
; 63(24): 15821-15851, 2020 12 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33290061
15.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators.
J Med Chem
; 63(19): 11169-11194, 2020 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32946228
16.
Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors.
J Med Chem
; 63(7): 3634-3664, 2020 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32176488
17.
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign.
Eur J Med Chem
; 189: 112047, 2020 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31982652
18.
Brain-wide Mapping of Endogenous Serotonergic Transmission via Chemogenetic fMRI.
Cell Rep
; 21(4): 910-918, 2017 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-29069598
19.
Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Cell Rep
; 39(4): 110760, 2022 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35476990
20.
Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies.
Eur J Med Chem
; 109: 216-37, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26774927